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Table 2 Comparison of overall lipid subclass concentrations between NAFLD cases and healthy controls*

From: Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico

Lipid class

Folda

P-value

Model 1b

Model 2c

Model 3d

Model 4e

Model 5f

Model 6g

CE

0.941

< 0.01

< 0.01

< 0.01

< 0.01

< 0.01

< 0.01

CER

1.503

0.19

0.11

0.12

0.47

0.35

0.08

DAG

1.174

0.26

0.23

0.95

0.43

0.35

0.94

FFA

1.013

0.26

0.24

0.63

0.43

0.38

0.62

HCER

1.168

0.64

0.66

0.95

0.86

0.88

0.94

LCER

0.739

0.97

0.97

0.95

0.86

0.88

0.12

LPC

0.960

0.01

0.03

0.09

0.06

0.14

0.94

LPE

0.972

0.94

0.97

0.84

0.98

0.88

0.94

PC

0.990

0.97

0.97

0.95

0.86

0.88

0.20

SM

0.975

0.03

0.03

0.18

0.06

0.10

0.94

TAG

1.372

0.19

0.20

0.95

0.24

0.26

0.81

  1. * Results presented are corrected for False Discovery Rate
  2. a Quotient of sum of all log-transformed lipid values in cases divided by sum of all log-transformed lipid values in controls
  3. b Adjusted for age and sex
  4. c Adjusted for age, sex, and PNPLA3 genotype
  5. d Adjusted for age, sex, diabetes, and metabolic syndrome status
  6. e Adjusted for age, sex, and BMI category
  7. f Adjusted for age, sex, BMI category, and PNPLA3 genotype
  8. g Adjusted for age, sex, diabetes, metabolic syndrome status, and PNPLA3 genotype
  9. Abbreviations: NAFLD nonalcoholic fatty liver disease, CE cholesterol ester, CER ceramide, DAG diacylglycerol, FFA free fatty acid, HCER hexosylceramide, LCER lactosylceramide, LPC lysophosphatidylcholine, LPE lysophosphatidylethanolamine, PC phosphatidylcholine, SM sphingomyelin, TAG triacylglycerol
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Lipids in Health and Disease

ISSN: 1476-511X