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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients

Fig. 1

Identifying differentially expressed miRNA in cachexia and non-cachexia cancer patients. a. The differentially expressed miRNA numbers in miRNA sequencing. b and c. The heatmap and volcano plots of the differentially expressed miRNAs in miRNA sequencing. d. Enrichment analysis top 20 in KEGG database (sorted by - log10P value of each entry) e. qPCR analyses of 11 differential miRNAs with minimum P-value in CAC groups. (non-cachexia groups’ relative expression was 1). f and g. qPCR analyses of miR-410-3p in CAC and non-cachexia groups and the correlation analysis of miR-410-3p expression and proportion of weight loss in CAC patients. All results are expressed as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001

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