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Table 1 Clinical correlation of miR-410-3p expression in cancer patients

From: miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients

 

miR-410-3p

  

Features

Low (n = 30)

Higha (n = 30)

t/χ2

P

Gender

  

4.8

0.028

Male

16

24

  

Female

14

6

  

Age (years)

  

0.606

0.436

> 65

12

15

  

≤ 65

18

15

  

Tumor stage

  

8.531

0.003

I + II

17

6

  

III + IV

13

24

  

Weight (kg)

62.3 ± 8.06

59.73 ± 11.6

0.834

0.410

BMI (kg/m2)

22.6 ± 2.55

21.71 ± 2.2

1.144

0.260

Body weight loss (%)

0.23 ± 0.09

9.76 ± 4.12

11.862

< 0.001

IL-6 (pg/mL)

3.81 ± 1.78

6.96 ± 2.74

2.385

0.024

TNF-a (pg/mL)

9.57 ± 5.98

12.45 ± 7.83

1.164

0.253

TP (g/L)

65.21 ± 5.44

64.27 ± 4.77

0.57

0.574

ALB (g/L)

41.57 ± 4.41

39.1 ± 3.92

1.947

0.044

  1. aAccording to the median expression level of miR-410-3p in all patients, the expression with lower than 50th percentile was classified as low expression group; the patients with higher than 50th percentile was classified as high expression group