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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

Fig. 1

Regional association plot for the APOC3 common variant rs5128 showing association with plasma triglyceride levels. SNPs from the APOC3 region are plotted by position on the x-axis versus association with triglyceride levels (−log10 P) on the y-axis. The black diamond signifies p-values of the studied SNP (rs5128) in Sikhs and in the combined analysis using replication studies. Global meta-analysis results are depicted by a red diamond at the top of the plot. The SNPs surrounding the most significant SNP are color-coded to reflect their LD with this SNP. We present linkage disequilibrium (LD) using the GIH panel (Gujarati Indians in Houston), the closest HapMap population to the Sikhs. At the bottom of the plot, the locations of known genes in the region are shown

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Lipids in Health and Disease

ISSN: 1476-511X