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Table 1 Baseline characteristics of the study subjects

From: Triglyceride glucose-body mass index and the risk of diabetes: a general population-based cohort study

 

TyG-BMI quintile

P-value

Q1(96.68-164.00)

Q2(164.00-184.00)

Q3(184.00-204.10)

Q4(204.11-228.11)

Q5(228.11-477.08)

No. of subjects

23332

23332

23333

23331

23333

 

Age (years)

35.00 (31.00-42.00)

39.00 (33.00-49.00)

43.00 (35.00-54.00)

46.00 (36.00-57.00)

46.00 (37.00-58.00)

<0.001

Sex

     

<0.001

 Male

5899 (25.28%)

9418 (40.37%)

13306 (57.03%)

16083 (68.93%)

18053 (77.37%)

 

 Female

17433 (74.72%)

13914 (59.63%)

10027 (42.97%)

7248 (31.07%)

5280 (22.63%)

 

Family history of diabetes

492 (2.11%)

563 (2.41%)

522 (2.24%)

517 (2.22%)

540 (2.31%)

<0.001

Height (cm)

164.07 (7.44)

164.99 (8.13)

166.43 (8.49)

167.52 (8.39)

168.44 (8.30)

<0.001

Weight (kg)

52.02 (5.79)

58.69 (6.53)

64.41 (7.32)

70.03 (7.83)

79.24 (10.26)

<0.001

BMI (kg/m2)

19.29 (1.30)

21.50 (1.12)

23.19 (1.20)

24.89 (1.32)

27.86 (2.36)

<0.001

SBP (mmHg)

110.29 (13.49)

114.84 (14.86)

119.76 (15.65)

123.68 (16.16)

128.57 (16.60)

<0.001

DBP (mmHg)

68.00 (63.00-74.00)

70.00 (64.00-77.00)

74.00 (67.00-81.00)

76.00 (70.00-84.00)

80.00 (73.00-88.00)

<0.001

FPG (mmol/L)

4.69 (0.53)

4.83 (0.54)

4.94 (0.57)

5.05 (0.60)

5.23 (0.64)

<0.001

TG (mmol/L)

0.66 (0.51-0.84)

0.87 (0.69-1.11)

1.10 (0.85-1.45)

1.44 (1.10-1.90)

2.07 (1.51-2.88)

<0.001

TyG

7.81 (0.38)

8.11 (0.38)

8.38 (0.41)

8.67 (0.43)

9.08 (0.52)

<0.001

TC (mmol/L)

4.43 (0.79)

4.63 (0.83)

4.79 (0.87)

4.95 (0.89)

5.14 (0.92)

<0.001

HDL-C (mmol/L)

1.53 (0.31)

1.45 (0.29)

1.36 (0.28)

1.30 (0.27)

1.23 (0.27)

<0.001

LDL-C (mmol/L)

2.50 (0.59)

2.68 (0.63)

2.81 (0.67)

2.91 (0.68)

2.95 (0.72)

<0.001

ALT (IU/L)

13.00 (10.20-17.00)

15.00 (11.50-20.30)

18.00 (13.60-25.00)

22.00 (16.00-31.28)

29.00 (20.10-43.70)

<0.001

AST (IU/L)

19.90 (17.00-23.00)

20.70 (17.70-24.20)

22.00 (18.70-26.00)

23.00 (19.90-28.00)

25.70 (21.20-32.00)

<0.001

BUN (mmol/L)

4.28 (3.60-5.09)

4.44 (3.73-5.25)

4.60 (3.88-5.42)

4.72 (4.02-5.53)

4.79 (4.06-5.60)

<0.001

Scr (mmol/L)

60.30 (53.30-70.90)

64.70 (55.60-77.60)

70.90 (59.00-82.00)

74.90 (63.20-84.30)

76.10 (66.00-85.80)

<0.001

Smoking status

     

<0.001

 Non

556 (2.38%)

859 (3.68%)

1199 (5.14%)

1719 (7.37%)

2325 (9.96%)

 

 Former

95 (0.41%)

172 (0.74%)

294 (1.26%)

362 (1.55%)

403 (1.73%)

 

 Current

5106 (21.88%)

5022 (21.52%)

4995 (21.41%)

4861 (20.83%)

4665 (19.99%)

 

 Not recorded

17575 (75.33%)

17279 (74.06%)

16845 (72.19%)

16389 (70.25%)

15940 (68.32%)

 

Drinking status

     

<0.001

 Non

50 (0.21%)

82 (0.35%)

151 (0.65%)

233 (1.00%)

356 (1.53%)

 

 Former

483 (2.07%)

759 (3.25%)

1160 (4.97%)

1426 (6.11%)

1696 (7.27%)

 

 Current

5224 (22.39%)

5212 (22.34%)

5177 (22.19%)

5283 (22.64%)

5341 (22.89%)

 

 Not recorded

17575 (75.33%)

17279 (74.06%)

16845 (72.19%)

16389 (70.25%)

15940 (68.32%)

 
  1. Values were expressed as mean (SD) or medians (quartile interval) or n (%). The differences among quintiles were evaluated by one-way ANOVA and Tukey’s HSD test or the Kruskal–Wallis test and Steel–Dwass test. After making a pairwise comparison between the quintiles, the results showed that there were significant differences among all groups (P < 0.05)
  2. Abbreviations: BMI Body mass index, SBP systolic blood pressure, DBP diastolic blood pressure FPG fasting plasma glucose, TG triglyceride, TyG the triglyceride-glucose index, TyG-BMI triglyceride glucose-body mass index, TC total cholesterol, LDL-C low-density lipid cholesterol, BUN blood urea nitrogen, Scr serum creatinine, ALT alanine aminotransferase, AST aspartate aminotransferase
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Lipids in Health and Disease

ISSN: 1476-511X