Table 4 Hazard ratios and 95% confidence intervals of baseline low density lipoprotein cholesterol categories for all-cause mortality by age group
LDL cholesterol | Prevalence of death/total (%) | Non-adjusted HR (95% CI) | Gender and age-adjusted HR (95% CI) | Multivariable-adjusted HR (95% CI) a |
|---|---|---|---|---|
<  55 years of age (n = 788) | ||||
 Very low | 4/65 (6.2) | 7.03 (0.79–62.9) | 6.47 (0.70–59.8) | 4.91 (0.49–49.6) |
 Low | 1/168 (0.6) | 0.71 (0.04–11.3) | 0.70 (0.04–11.3) | 0.65 (0.04–10.9) |
 Medium | 13/431 (3.0) | 3.65 (0.48–27.9) | 4.03 (0.52–30.9) | 3.19 (0.40–25.4) |
 High | 1/124 (0.8) | 1.00 | 1.00 | 1.00 |
P-value | 0.041 | 0.108 | 0.123 | 0.226 |
≥ 55 and < 65 years of age (n = 783) | ||||
 Very low | 4/28 (14.3) | 8.19 (1.83–36.6) | 6.66 (1.40–31.7) | 7.04 (1.40–35.5) |
 Low | 9/99 (9.1) | 5.74 (1.55–21.2) | 4.66 (1.22–17.8) | 4.33 (1.12–16.8) |
 Medium | 19/468 (4.1) | 2.55 (0.75–8.62) | 2.29 (0.67–7.80) | 2.24 (0.65–7.65) |
 High | 3/188 (1.6) | 1.00 | 1.00 | 1.00 |
P-value | 0.002 | 0.009 | 0.042 | 0.057 |
≥ 65 and < 75 years of age (n = 1395) | ||||
 Very low | 9/52 (17.3) | 2.76 (1.24–6.15) | 2.34 (1.02–5.39) | 2.52 (1.08–5.93) |
 Low | 18/179 (10.1) | 1.62 (0.84–3.11) | 1.43 (0.73–2.79) | 1.37 (0.70–2.69) |
 Medium | 60/872 (6.9) | 1.12 (0.66–1.89) | 1.02 (0.60–1.74) | 0.93 (0.54–1.59) |
 High | 18/292 (6.2) | 1.00 | 1.00 | 1.00 |
P-value | 0.007 | 0.037 | 0.109 | 0.044 |
≥ 75 years of age (n = 718) | ||||
 Very low | 16/36 (44.4) | 3.03 (1.61–5.71) | 2.53 (1.33–4.84) | 2.13 (1.09–4.16) |
 Low | 34/109 (31.2) | 2.27 (1.35–3.84) | 1.99 (1.17–3.39) | 1.75 (1.01–3.05) |
 Medium | 93/441 (21.1) | 1.27 (0.81–1.98) | 1.22 (0.78–1.92) | 1.09 (0.68–1.73) |
 High | 24/132 (18.2) | 1.00 | 1.00 | 1.00 |
P-value | <  0.001 | <  0.001 | 0.004 | 0.021 |