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Table 3 Univariate and multivariate analyses to identify a correlation between prognostic factors and OS in CRC patients

From: Expression and prognostic significance of Niemann-Pick C1-Like 1 in colorectal cancer: a retrospective cohort study

  Univariate analysis Multivariate analysis
HRa (95% CIb) P-value HRa (95% CIb) P-value
Age ≥ 70 (vs. < 70) 1.669 (1.103–2.524) 0.015 2.286 (1.485–3.519) < 0.001
Sex Male (vs. Female) 0.872 (0.579–1.3174) 0.513 0.942 (0.622–1.426) 0.776
Stage III + IV (vs. I + II) 3.150 (2.044–4.855) < 0.001 3.698 (2.366–5.779) < 0.001
NPC1L1 High (vs. Low) 1.618 (1.071–2.445) 0.022 1.618 (1.067–2.453) 0.024
  1. aHR hazard ratio, bCI confidence interval, OS overall survival, CRC colorectal cancer, NPC1L1 Niemann-Pick C1-Like 1