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Table 3 Univariate and multivariate analyses to identify a correlation between prognostic factors and OS in CRC patients

From: Expression and prognostic significance of Niemann-Pick C1-Like 1 in colorectal cancer: a retrospective cohort study

 

Univariate analysis

Multivariate analysis

HRa (95% CIb)

P-value

HRa (95% CIb)

P-value

Age ≥ 70 (vs. < 70)

1.669 (1.103–2.524)

0.015

2.286 (1.485–3.519)

< 0.001

Sex Male (vs. Female)

0.872 (0.579–1.3174)

0.513

0.942 (0.622–1.426)

0.776

Stage III + IV (vs. I + II)

3.150 (2.044–4.855)

< 0.001

3.698 (2.366–5.779)

< 0.001

NPC1L1 High (vs. Low)

1.618 (1.071–2.445)

0.022

1.618 (1.067–2.453)

0.024

  1. aHR hazard ratio, bCI confidence interval, OS overall survival, CRC colorectal cancer, NPC1L1 Niemann-Pick C1-Like 1