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Table 4 Univariate and multivariate analyses to identify a correlation between NPC1L1 expression and other prognostic factors of CRC

From: Expression and prognostic significance of Niemann-Pick C1-Like 1 in colorectal cancer: a retrospective cohort study

  Univariate analysis Multivariate analysis
HRa (95% CIb) P-value HRa (95% CIb) P-value
NPC1L1 High (vs. Low) 1.618 (1.071–2.445) 0.022 1.557 (1.025–2.363) 0.038
VEGF-A High (vs. Low) 1.796 (1.185–2.723) 0.005 1.758 (1.150–2.686) 0.009
MACC1 High (vs. Low) 1.567 (1.033–2.375) 0.034 1.421 (0.928–2.178) 0.106
TGF-β1 High (vs. Low) 1.369 (0.908–2.064) 0.132 1.502 (0.990–2.278) 0.056
  1. aHR hazard ratio, bCI confidence interval, CRC colorectal cancer, NPC1L1 Niemann-Pick C1-Like 1, TGF-β1 transforming growth factor beta 1, MACC1 metastasis-associated in colon cancer 1, VEGF-A vascular endothelial growth factor-A