Polymorphisms, n (%) | Overall (n=2218) | Han (n=1044) | Uygur (n=828) | Kazak (n=113) | Hui (n=138) | Tatar (n=39) | Kirgiz (n=36) | Sibe (n=20) | P value |
---|---|---|---|---|---|---|---|---|---|
ABCB1 C3435T | |||||||||
 CC | 671 (30.3) | 359 (34.4) a | 203 (24.5) b | 33 (29.2) ab | 42 (30.4) ab | 16 (41.0) ab | 11 (30.6) ab | 7 (35.0) ab | < .001 |
 CT | 1103 (49.7) | 512 (49.0) | 415 (50.1) | 57 (50.4) | 75 (54.3) | 16 (41.0) | 17 (47.2) | 11 (55.0) | |
 TT | 444 (20.0) | 173 (16.6) a | 210 (25.4) b | 23 (20.4) ab | 21 (15.2) ab | 7 (18.0) ab | 8 (22.2) ab | 2 (10.0) ab | |
 C allele | 2445 (55.1) | 1230 (58.9) a | 821 (49.6) b | 123 (54.4) ab | 159 (57.6) ab | 48 (61.5) ab | 39 (54.2) ab | 25 (62.5) ab | < .001 |
 T allele | 1991 (44.9) | 858 (41.1) a | 835 (50.4) b | 103 (45.6) ab | 117 (42.4) ab | 30 (38.5) ab | 33 (45.8) ab | 15 (37.5) ab | |
ABCB1 G2677T | |||||||||
 GG | 606 (27.3) | 297 (28.4) | 210 (25.4) | 36 (31.9) | 36 (26.1) | 12 (30.8) | 8 (22.2) | 7 (35.0) | 0.586 |
 GT | 956 (43.1) | 429 (41.1) | 365 (44.1) | 51 (45.1) | 68 (49.3) | 17 (43.6) | 17 (47.2) | 9 (45.0) | |
 TT | 656 (29.6) | 318 (30.5) | 253 (30.6) | 26 (23.0) | 34 (24.6) | 10 (25.6) | 11 (30.6) | 4 (20.0) | |
 G allele | 2168 (48.9) | 1023 (49.0) | 785 (47.4) | 123 (54.4) | 140 (50.7) | 41 (52.6) | 33 (45.8) | 23 (57.5) | 0.37 |
 T allele | 2268 (51.1) | 1065 (51.0) | 871 (52.6) | 103 (45.6) | 136 (49.3) | 37 (47.4) | 39 (54.2) | 17 (42.5) | |
SLCO1B1 T521C | |||||||||
 TT | 1737 (78.3) | 813 (77.9) | 655 (79.1) | 87 (77.0) | 111 (80.4) | 29 (74.4) | 27 (75.0) | 15 (75.0) | 0.326 |
 CT | 450 (20.3) | 219 (21.0) | 161 (19.4) | 22 (19.5) | 27 (19.6) | 9 (23.1) | 7 (19.4) | 5 (25.0) | |
 CC | 31 (1.4) | 12 (1.1) | 12 (1.4) | 4 (3.5) | 0 (0) | 1 (2.6) | 2 (5.6) | 0 (0) | |
 T allele | 3924 (88.5) | 1845 (88.4) | 1471 (88.8) | 196 (86.7) | 249 (90.2) | 67 (85.9) | 61 (84.7) | 35 (87.5) | 0.717 |
 C allele | 512 (11.5) | 243 (11.6) | 185 (11.2) | 30 (13.3) | 27 (9.8) | 11 (14.1) | 11 (15.3) | 5 (12.5) |