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Table 5 Polymorphisms of ABCB1 and SLCO1B1 across ethnicities

From: Prevalence of dyslipidemia and gene polymorphisms of ABCB1 and SLCO1B1 in Han, Uygur, Kazak, Hui, Tatar, Kirgiz, and Sibe populations with coronary heart disease in Xinjiang, China

Polymorphisms, n (%)

Overall (n=2218)

Han (n=1044)

Uygur (n=828)

Kazak (n=113)

Hui (n=138)

Tatar (n=39)

Kirgiz (n=36)

Sibe (n=20)

P value

ABCB1 C3435T

 CC

671 (30.3)

359 (34.4) a

203 (24.5) b

33 (29.2) ab

42 (30.4) ab

16 (41.0) ab

11 (30.6) ab

7 (35.0) ab

< .001

 CT

1103 (49.7)

512 (49.0)

415 (50.1)

57 (50.4)

75 (54.3)

16 (41.0)

17 (47.2)

11 (55.0)

 TT

444 (20.0)

173 (16.6) a

210 (25.4) b

23 (20.4) ab

21 (15.2) ab

7 (18.0) ab

8 (22.2) ab

2 (10.0) ab

 C allele

2445 (55.1)

1230 (58.9) a

821 (49.6) b

123 (54.4) ab

159 (57.6) ab

48 (61.5) ab

39 (54.2) ab

25 (62.5) ab

< .001

 T allele

1991 (44.9)

858 (41.1) a

835 (50.4) b

103 (45.6) ab

117 (42.4) ab

30 (38.5) ab

33 (45.8) ab

15 (37.5) ab

ABCB1 G2677T

 GG

606 (27.3)

297 (28.4)

210 (25.4)

36 (31.9)

36 (26.1)

12 (30.8)

8 (22.2)

7 (35.0)

0.586

 GT

956 (43.1)

429 (41.1)

365 (44.1)

51 (45.1)

68 (49.3)

17 (43.6)

17 (47.2)

9 (45.0)

 TT

656 (29.6)

318 (30.5)

253 (30.6)

26 (23.0)

34 (24.6)

10 (25.6)

11 (30.6)

4 (20.0)

 G allele

2168 (48.9)

1023 (49.0)

785 (47.4)

123 (54.4)

140 (50.7)

41 (52.6)

33 (45.8)

23 (57.5)

0.37

 T allele

2268 (51.1)

1065 (51.0)

871 (52.6)

103 (45.6)

136 (49.3)

37 (47.4)

39 (54.2)

17 (42.5)

SLCO1B1 T521C

 TT

1737 (78.3)

813 (77.9)

655 (79.1)

87 (77.0)

111 (80.4)

29 (74.4)

27 (75.0)

15 (75.0)

0.326

 CT

450 (20.3)

219 (21.0)

161 (19.4)

22 (19.5)

27 (19.6)

9 (23.1)

7 (19.4)

5 (25.0)

 CC

31 (1.4)

12 (1.1)

12 (1.4)

4 (3.5)

0 (0)

1 (2.6)

2 (5.6)

0 (0)

 T allele

3924 (88.5)

1845 (88.4)

1471 (88.8)

196 (86.7)

249 (90.2)

67 (85.9)

61 (84.7)

35 (87.5)

0.717

 C allele

512 (11.5)

243 (11.6)

185 (11.2)

30 (13.3)

27 (9.8)

11 (14.1)

11 (15.3)

5 (12.5)

  1. a and b denote the difference of ethnic groups by χ2 test at 0.05