Fig. 1
From: Negative correlation between endoglin levels and coronary atherosclerosis
Exploring gene expression changes in FH patients using the GEO dataset. Endoglin expression was significantly down-regulated in FH patients, and TGFβR1/2 itself did not change significantly. In the downstream SMAD family, SMAD2, SMAD3, and SMAD4 were down-regulated in patients, while SMAD6 was up-regulated significantly (*P < 0.05, **P < 0.01, ***P < 0.001)