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Table. 2 Odds ratios (95 % CI) for HUA according to continuous and tertiles of lipid ratios

From: The association of lipid ratios with hyperuricemia in a rural Chinese hypertensive population

   

Crude model

 

Adjusted model

 

Variables

N

Events, n (%)

OR (95 %CI)

P value

OR (95 %CI)

P value

TC/HDL-C ratio (Per 1 SD increase)

14,227

6320 (44.42 %)

1.37 (1.32, 1.43)

< 0.001

1.35 (1.28, 1.41)

< 0.001

Tertiles of TC/HDL-C ratio

     

T1 (< 2.75)

4,742

1795 (37.85 %)

Reference

 

Reference

 

T2 (2.75–4.12)

4,742

2032 (42.85 %)

1.23 (1.13, 1.34)

< 0.001

1.32 (1.20, 1.46)

< 0.001

T3 (≥ 4.12)

4,743

2493 (52.56 %)

1.82 (1.68, 1.97)

< 0.001

1.78 (1.61, 1.97)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 

TG/HDL-C ratio (Per 1 SD increase)

14,227

6320 (44.42 %)

1.26 (1.22, 1.30)

< 0.001

1.27 (1.23, 1.32)

< 0.001

Tertiles of TG/HDL-C ratio

     

T1 (< 0.62)

4,740

1773 (37.41 %)

Reference

 

Reference

 

T2 (0.62–2.03)

4,744

2002 (42.20 %)

1.22 (1.13, 1.33)

< 0.001

1.30 (1.17, 1.43)

< 0.001

T3 (≥ 2.03)

4,743

2545 (53.66 %)

1.94 (1.79, 2.10)

< 0.001

2.09 (1.88, 2.32)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 

LDL-C/HDL-C ratio (Per 1 SD increase)

14,227

6320 (44.42 %)

1.45 (1.38, 1.53)

< 0.001

1.40 (1.32, 1.50)

< 0.001

Tertiles of LDL/HDL-C ratio

     

T1 (< 1.49)

4,741

1817 (38.33 %)

Reference

 

Reference

 

T2 (1.49–2.53)

4,743

2040 (43.01 %)

1.21 (1.12, 1.32)

< 0.001

1.31 (1.19, 1.45)

< 0.001

T3 (≥ 2.53)

4,743

2463 (51.93 %)

1.74 (1.60, 1.89)

< 0.001

1.65 (1.49, 1.82)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 

non-HDL-C (Per 1 mmol/L increase)

14,227

6320 (44.42 %)

1.19 (1.15, 1.23)

< 0.001

1.33 (1.28, 1.39)

< 0.001

Tertiles of non-HDL-C

      

T1 (< 2.81)

4,742

1933 (40.76 %)

Reference

 

Reference

 

T2 (2.81–4.36)

4,732

2020 (42.69 %)

1.08 (1.00, 1.17)

0.0575

1.29 (1.17, 1.42)

< 0.001

T3 (≥ 4.36)

4,753

2367 (49.80 %)

1.44 (1.33, 1.56)

< 0.001

1.89 (1.71, 2.09)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 
  1. Abbreviations: OR, odds ratio; CI, confidence interval; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; non-HDL-C, non-high-density lipoprotein cholesterol
  2. Adjusted model: adjusted for age, sex, BMI, SBP, DBP, current smoking, alcohol use, eGFR, Hcy, diabetes mellitus, antihypertensive drugs, and lipid-lowering drugs