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Table 3 Odds ratio (OR) and 95 % confidence intervals (CI) for breast cancer according to quartile of fat intake in women

From: Association between dietary fat and fat subtypes with the risk of breast cancer in an Iranian population: a case-control study

  Quartile of intake  
  1 2 3 4 P value
  Total fat  
All women 107/126 105/124 125/125 133/126  
Age and energy adjusted OR 1 1.07 (0.72–1.57) 1.36 (0.92–2.01) 1.40 (0.97–2.02) 0.03
Multivariable OR 1 1.11 (0.74–1.67) 1.44 (0.95–2.16) 1.50 (1.02–2.20) 0.01
Premenopausal women 68/80 71/67 84/91 81/88  
Age and energy adjusted OR 1 1.46 (0.89–2.40) 1.40 (0.86–2.26) 1.27 (0.80-2.00) 0.4
Multivariable OR 1 1.53 (0.92–2.57) 1.43 (0.86–2.39) 1.31 (0.81–2.12) 0.36
Postmenopausal women 36/45 32/55 40/32 49/33  
Age and energy adjusted OR 1 0.66 (0.34–1.26) 1.40 (0.71–2.76) 1.88 (1.00-3.54) 0.008
Multivariable OR 1 0.66 (0.33–1.32) 1.62 (0.78–3.34) 2.16 (1.11–4.22) 0.003
  Animal fat  
All women 107/126 120/125 118/123 126/127  
Age and energy adjusted OR 1 1.19 (0.81–1.75) 1.28 (0.86–1.89) 1.28 (0.88–1.83) 0.19
Multivariable OR 1 1.10 (0.74–1.65) 1.38 (0.92–2.08) 1.28 (0.87–1.88) 0.12
Premenopausal women 70/84 76/76 78/73 81/93  
Age and energy adjusted OR 1 1.36 (0.84–2.19) 1.50 (0.92–2.46) 1.14 (0.73–1.78) 0.59
Multivariable OR 1 1.26 (0.76–2.08) 1.53 (0.91–2.57) 1.11 (0.69–1.77) 0.62
Postmenopausal women 33/41 42/48 39/45 43/31  
Age and energy adjusted OR 1 0.99 (0.52–1.88) 0.99 (0.50–1.92) 1.69 (0.87–3.28) 0.12
Multivariable OR 1 0.93 (0.47–1.86) 1.19 (0.59–2.42) 1.89 (0.93–3.81) 0.05
  Vegetable fat  
All women 119/126 142/123 85/123 130/129  
Age and energy adjusted OR 1 1.34 (0.92–1.95) 0.80 (0.53–1.22) 1.24 (0.86–1.78) 0.72
Multivariable OR 1 1.41 (0.95–2.08) 0.90 (0.59–1.39) 1.30 (0.89–1.91) 0.51
Premenopausal women 77/76 89/77 55/80 88/93  
Age and energy adjusted OR 1 1.30 (0.81–2.09) 0.83 (0.50–1.40) 1.13 (0.72–1.77) 0.97
Multivariable OR 1 1.45 (0.88–2.39) 0.92 (0.53–1.59) 1.20 (0.74–1.94) 0.87
Postmenopausal women 41/50 49/42 28/42 40/31  
Age and energy adjusted OR 1 1.34 (0.71–2.52) 0.73 (0.436–1.47) 1.56 (0.82–2.95) 0.45
Multivariable OR 1 1.29 (0.66–2.51) 0.82 (0.39–1.71) 1.68 (0.85–3.31) 0.29
  Total SFA  
All women 106/126 108/123 131/124 124/128  
Age and energy adjusted OR 1 1.08 (0.74–1.59) 1.46(0.99–2.14) 1.27 (0.88–1.83) 0.09
Multivariable OR 1 1.17 (0.78–1.74) 1.55 (1.04–2.32) 1.28 (0.87–1.88) 0.11
Premenopausal women 67/79 73/77 85/82 78/88  
Age and energy adjusted OR 1 1.15 (0.72–1.86) 1.53 (0.95–2.48) 1.17 (0.74–1.86) 0.34
Multivariable OR 1 1.26 (0.77–2.08) 1.50 (0.90–2.47) 1.14 (0.71–1.85) 0.52
Postmenopausal women 36/46 33/45 43/37 45/37  
Age and energy adjusted OR 1 0.87 (0.45–1.67) 1.40 (0.74–2.67) 1.56 (0.83–2.92) 0.07
Multivariable OR 1 0.96 (0.48–1.93) 1.75 (0.88–3.46) 1.70 (0.88–3.30) 0.04
  Total MUFA  
All women 109/126 114/124 120/124 131/127  
Age and energy adjusted OR 1 1.14 (0.78–1.68) 1.27 (0.86–1.88) 1.29 (0.90–1.86) 0.13
Multivariable OR 1 1.20 (0.81–1.79) 1.32 (0.88–1.98) 1.34 (0.92–1.96) 0.11
Premenopausal women 70/82 81/77 78/79 78/88  
Age and energy adjusted OR 1 1.48 (0.92–2.38) 1.56 (0.95–2.55) 1.17 (0.74–1.84) 0.55
Multivariable OR 1 1.51 (0.92–2.48) 1.53 (0.91–2.58) 1.19 (0.74–1.91) 0.57
Postmenopausal women 36/42 31/46 39/42 52/35  
Age and energy adjusted OR 1 0.68 (0.35–1.34) 0.98 (0.51–1.89) 1.70 (0.91–3.18) 0.04
Multivariable OR 1 0.74 (0.36–1.50) 1.09 (0.54–2.20) 1.85 (0.95–3.61) 0.03
  Total PUFA  
All women 98/126 121/123 130/124 123/128  
Age and energy adjusted OR 1 1.33 (0.9–1.95) 1.54 (1.05–2.26) 1.36 (0.94–1.97) 0.08
Multivariable OR 1 1.43 (0.96–2.14) 1.70 (1.13–2.55) 1.50 (1.02–2.22) 0.03
Premenopausal women 67/76 73/72 82/86 84/92  
Age and energy adjusted OR 1 1.29 (0.80–2.10) 1.31 (0.81–2.11) 1.16 (0.74–1.83) 0.56
Multivariable OR 1 1.45 (0.87–2.40) 1.48 (0.90–2.45) 1.28 (0.79–2.07) 0.37
Postmenopausal women 30/49 44/49 47/35 36/32  
Age and energy adjusted OR 1 1.42 (0.74–2.72) 2.11 (1.08–4.15) 1.90 (0.97–3.70) 0.02
Multivariable OR 1 1.41 (0.70–2.85) 2.42 (1.17–5.01) 2.12 (1.05–4.27) 0.01
  Total Cholesterol  
All women 132/126 110/124 117/125 116/126  
Age and energy adjusted OR 1 0.94 (0.65–1.36) 1.02 (0.70–1.49) 0.98 (0.68–1.40) 0.96
Multivariable OR 1 1.02 (0.69–1.51) 1.08 (0.72–1.60) 1.03 (0.71–1.52) 0.79
Premenopausal women 74/76 71/82 80/89 83/79  
Age and energy adjusted OR 1 1.04 (0.65–1.67) 1.12 (0.70–1.80) 1.26 (0.80–2.01) 0.27
Multivariable OR 1 1.09 (0.66–1.80) 1.19 (0.72–1.96) 1.29 (0.79–2.09) 0.27
Postmenopausal women 54/49 38/39 33/32 33/45  
Age and energy adjusted OR 1 0.82 (0.44–1.50) 0.89 (0.46–1.69) 0.65 (0.35–1.18) 0.20
Multivariable OR 1 1.02 (0.54–1.95) 0.91 (0.46–1.80) 0.75 (0.40–1.41) 0.35
  1. Multivariable model: additionally, adjusted for cigar smoking, marital status, alcohol consumption, physical activity, education, family history of breast cancer, parity, and BMI
  2. SFA: saturated fatty acids, MUFA: monounsaturated fatty acids, PUFA: polyunsaturated fatty acids
  3. All quantities for fatty acids were reported as grams