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Table 4 Cholesterol content in subfractions of lipoproteins at baseline and after lipid-lowering therapy by the Sampson equation

From: Main differences between two highly effective lipid-lowering therapies in subclasses of lipoproteins in patients with acute myocardial infarction

Lipoproteins

Simvastatin plus ezetimibe

N = 50

Rosuvastatin monotherapy

N = 51

P value

At baseline (D1)

 LDL-C

124 (111–154)

127 (101–147)

0.58

 VLDL-C

24 (17–38)

27 (17–43)

0.55

 lbLDL-C

88 (69–110)

84 (62–99)

0.32

 sdLDL-C

41 (33–50)

42 (31–55)

0.94

After 30 days (D30)

 LDL-C

54 (39–76)

58 (46–80)

0.23

 VLDL-C

19 (15–27)

21 (15–28)

0.58

 lbLDL-C

31 (21–45)

36 (26–49)

0.18

 sdLDL-C

23 (17–30)

23 (20–30)

0.36

  1. Values (mg/dL) are medians (IQRs) of cholesterol from subfractions of large and buoyant (lbLDL) or small and dense (sdLDL) lipoproteins obtained at baseline and after 30 days based on the Sampson equation from the standard lipid panel. Data were compared by the Mann–Whitney U test