The usefulness of obesity and lipid-related indices to predict the presence of Non-alcoholic fatty liver disease

Sheng, Guotai; Lu, Song; Xie, Qiyang; Peng, Nan; Kuang, Maobin; Zou, Yang

doi:10.1186/s12944-021-01561-2

Lipids in Health and Disease

Table 5 Areas under the ROC curves for obesity and lipid-related indices as a predictor of nonalcoholic fatty liver disease in female subjects of different ages

From: The usefulness of obesity and lipid-related indices to predict the presence of Non-alcoholic fatty liver disease

	AUC	95%CI low	95%CI upp	Best threshold	Positive-LR	Negative-LR	Specificity	Sensitivity
Age>60years
BMI	0.8424	0.7447	0.9400	23.3334	5.8333	0.1944	0.8571	0.8333
WC	0.7525	0.6356	0.8694	80.2500	3.0196	0.4278	0.7792	0.6667
WHtR	0.7511	0.6357	0.8665	0.5258	0.4716	7.3915	0.8247	0.6111
TG	0.6825	0.5326	0.8325	1.1911	3.2906	0.5347	0.8312	0.5556
TyG	0.6843	0.5423	0.8264	8.5008	3.2906	0.5347	0.8312	0.5556
TyG-BMI	0.8853	0.8080	0.9625	185.5919	4.2778	0.0713	0.7792	0.9444
TyG-WC	0.8045	0.7033	0.9056	666.3764	4.1067	0.3979	0.8377	0.6667
TyG-WHtR	0.8023	0.7014	0.9032	3.9938	2.4889	0.1728	0.6429	0.8889
TG/HDL-C ratio	0.6659	0.5131	0.8188	0.9641	4.5294	0.5620	0.8896	0.5000
HSI	0.8506	0.7547	0.9466	34.3072	9.2685	0.3013	0.9221	0.7222
VAI	0.6685	0.5178	0.8191	1.8359	5.9231	0.5461	0.9156	0.5000
LAP	0.8014	0.7079	0.8950	11.8347	2.1079	0.1007	0.5519	0.9444
ABSI	0.5321	0.3973	0.6669	0.0782	1.4444	0.5556	0.5000	0.7222
BRI	0.7511	0.6357	0.8665	3.8560	3.4856	0.4716	0.8247	0.6111
COI	0.6118	0.4789	0.7448	1.2326	1.9861	0.4365	0.6364	0.7222
Age 46-60years
BMI	0.8198	0.7937	0.8459	22.7522	3.1495	0.3229	0.7605	0.7544
WC	0.8160	0.7913	0.8407	74.7500	2.3102	0.2516	0.6364	0.8399
WHtR	0.8244	0.7998	0.8490	0.4858	2.8061	0.3011	0.7210	0.7829
TG	0.7390	0.7086	0.7694	0.7734	2.0204	0.4100	0.6336	0.7402
TyG	0.7549	0.7256	0.7842	8.1052	2.2148	0.4162	0.6754	0.7189
TyG-BMI	0.8497	0.8276	0.8719	178.7047	2.9930	0.2088	0.7158	0.8505
TyG-WC	0.8494	0.8280	0.8707	607.7065	2.7895	0.2291	0.6989	0.8399
TyG-WHtR	0.8541	0.8331	0.8752	3.8790	2.8579	0.2314	0.7074	0.8363
TG/HDL-C ratio	0.7591	0.7304	0.7877	0.4955	2.1445	0.3788	0.6482	0.7544
HSI	0.8455	0.8226	0.8684	32.8451	3.4263	0.3107	0.7788	0.7580
VAI	0.7708	0.7431	0.7986	0.9154	2.2600	0.3775	0.6693	0.7473
LAP	0.8377	0.8155	0.8598	14.0538	2.9346	0.2961	0.7332	0.7829
ABSI	0.6234	0.5900	0.6567	0.0758	1.4818	0.6110	0.5533	0.6619
BRI	0.8244	0.7998	0.8490	3.0960	2.8061	0.3011	0.7210	0.7829
COI	0.7228	0.6931	0.7525	1.1619	1.7995	0.4134	0.5768	0.7616
Age 31-45years
BMI	0.9311	0.9156	0.9467	23.0613	6.3800	0.1744	0.8670	0.8488
WC	0.9113	0.8927	0.9298	75.3500	4.0862	0.1484	0.7837	0.8837
WHtR	0.9155	0.8975	0.9334	0.4719	4.1807	0.0970	0.7789	0.9244
TG	0.8296	0.7971	0.8621	0.7169	3.3271	0.3228	0.7746	0.7500
TyG	0.8404	0.8090	0.8719	7.9863	3.7081	0.3134	0.7977	0.7500
TyG-BMI	0.9436	0.9280	0.9592	179.6766	6.5608	0.1146	0.8626	0.9012
TyG-WC	0.9354	0.9191	0.9518	595.3694	5.1492	0.1129	0.8239	0.9070
TyG-WHtR	0.9343	0.9172	0.9515	3.8736	7.0991	0.1652	0.8796	0.8547
TG/HDL-C ratio	0.8453	0.8140	0.8767	0.4767	3.6570	0.2807	0.7870	0.7791
HSI	0.9169	0.8957	0.9381	33.1586	6.6599	0.1797	0.8734	0.8430
VAI	0.8542	0.8242	0.8842	0.9040	4.1209	0.2990	0.8166	0.7558
LAP	0.9281	0.9109	0.9454	10.0086	4.1807	0.0970	0.7789	0.9244
ABSI	0.5611	0.5192	0.6029	0.0713	1.1665	0.4503	0.2324	0.8953
BRI	0.9155	0.8975	0.9334	2.8477	.1807	0.0970	0.7789	0.9244
COI	0.7508	0.7166	0.7851	1.1610	2.2617	0.4166	0.6838	0.7151
Age 18-30years
BMI	0.9313	0.8531	1.0000	20.8195	3.9355	0.0000	0.7459	1.0000
WC	0.9584	0.9107	1.0000	72.1000	5.6308	0.0000	0.8224	1.0000
WHtR	0.9606	0.9217	0.9995	0.4619	7.1765	0.0000	0.8607	1.0000
TG	0.9288	0.8679	0.9897	0.7508	9.5065	0.1570	0.9098	0.8571
TyG	0.9391	0.8652	1.0000	8.0897	16.5113	0.1507	0.9481	0.8571
TyG-BMI	0.9575	0.9033	1.0000	160.0894	5.2286	0.0000	0.8087	1.0000
TyG-WC	0.9723	0.9357	1.0000	554.8238	7.4694	0.0000	0.8661	1.0000
TyG-WHtR	0.9742	0.9456	1.0000	3.5509	9.8919	0.0000	0.8989	1.0000
TG/HDL-C ratio	0.9465	0.8972	0.9958	0.4417	6.5357	0.0000	0.8470	1.0000
HSI	0.9157	0.8244	1.0000	29.6667	3.1826	0.0000	0.6858	1.0000
VAI	0.9575	0.9177	0.9972	0.8322	8.3182	0.0000	0.8798	1.0000
LAP	0.9801	0.9512	1.0000	8.4370	9.6316	0.0000	0.8962	1.0000
ABSI	0.6511	0.3609	0.9412	0.0759	3.1497	0.3695	0.7732	0.7143
BRI	0.9606	0.9217	0.9995	2.6718	7.1765	0.0000	0.8607	1.0000
COI	0.8158	0.6292	1.0000	1.1613	4.5074	0.3395	0.8415	0.7143

Abbreviations: AUC: area under the curve; other abbreviations as in Table 1.

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