The usefulness of obesity and lipid-related indices to predict the presence of Non-alcoholic fatty liver disease

Sheng, Guotai; Lu, Song; Xie, Qiyang; Peng, Nan; Kuang, Maobin; Zou, Yang

doi:10.1186/s12944-021-01561-2

Lipids in Health and Disease

Table 6 Areas under the ROC curves for obesity and lipid-related indices as a predictor of nonalcoholic fatty liver disease in male subjects of different ages

From: The usefulness of obesity and lipid-related indices to predict the presence of Non-alcoholic fatty liver disease

	AUC	95%CI low	95%CI upp	Best threshold	Positive-LR	Negative-LR	Specificity	Sensitivity
Age>60years
BMI	0.7965	0.7349	0.8582	23.7420	3.9130	0.3495	0.8175	0.7143
WC	0.7716	0.7118	0.8313	80.8000	2.1176	0.2400	0.5952	0.8571
WHtR	0.7639	0.7062	0.8215	0.4992	2.5205	0.3799	0.7103	0.7302
TG	0.6417	0.5679	0.7154	0.9258	1.5221	0.5755	0.5516	0.6825
TyG	0.6570	0.5853	0.7286	8.1646	1.5312	0.4516	0.4921	0.7778
TyG-BM	0.7913	0.7309	0.8518	194.1812	2.7222	0.3111	0.7143	0.7778
TyG-WC	0.7725	0.7101	0.8348	694.1685	2.4658	0.4022	0.7103	0.7143
TyG-WHtR	0.7679	0.7070	0.8287	3.9308	1.8689	0.1846	0.5159	0.9048
TG/HDL-C ratio	0.6515	0.5781	0.7250	0.8877	1.7882	0.5988	0.6627	0.6032
HSI	0.8381	0.7868	0.8894	31.2974	3.2615	0.2139	0.7421	0.8413
VAI	0.6623	0.5894	0.7351	1.1966	1.9733	0.5876	0.7024	0.5873
LAP	0.7481	0.6848	0.8114	13.4633	1.9065	0.3310	0.5754	0.8095
ABSI	0.5600	0.4805	0.6396	0.0759	1.2022	0.4638	0.2738	0.8730
BRI	0.7639	0.7062	0.8215	3.3445	2.5205	0.3799	0.7103	0.7302
COI	0.6557	0.5837	0.7277	1.1898	1.4752	0.3964	0.4405	0.8254
Age 46-60years
BMI	0.7855	0.7663	0.8047	23.5546	2.5148	0.4098	0.7196	0.7051
WC	0.7809	0.7616	0.8002	81.2500	2.1572	0.3190	0.6295	0.7992
WHtR	0.7859	0.7673	0.8045	0.4736	2.0365	0.2452	0.5786	0.8581
TG	0.7066	0.6845	0.7287	1.1121	1.9329	0.5332	0.6665	0.6447
TyG	0.7164	0.6946	0.7381	8.4415	1.9561	0.4908	0.6525	0.6798
TyG-BMI	0.8148	0.7968	0.8329	201.7871	3.2018	0.3671	0.7767	0.7149
TyG-WC	0.8081	0.7899	0.8264	711.4515	3.2917	0.3769	0.7862	0.7037
TyG-WHtR	0.8109	0.7929	0.8290	4.1294	2.8242	0.3320	0.7320	0.7570
TG/HDL-C ratio	0.7202	0.6986	0.7418	0.7396	1.7295	0.3940	0.5462	0.7848
HSI	0.8133	0.7953	0.8313	33.1439	2.8738	0.3466	0.7415	0.7430
VAI	0.7260	0.7046	0.7473	0.9306	1.7734	0.3761	0.5535	0.7918
LAP	0.7923	0.7736	0.8110	17.8721	2.4420	0.3504	0.6894	0.7584
ABSI	0.5696	0.5449	0.5942	0.0772	.2425	0.7989	0.5467	0.5632
BRI	0.7859	0.7673	0.8045	2.8766	2.0365	0.2452	0.5786	0.8581
COI	0.6828	0.6605	0.7051	1.2056	1.8572	0.5954	0.6794	0.5955
Age 31-45years
BMI	0.8337	0.8209	0.8466	23.4488	2.8721	0.3226	0.7343	0.7631
WC	0.8274	0.8145	0.8403	80.6500	2.6899	0.2950	0.7056	0.7918
WHtR	0.8385	0.8260	0.8509	0.4713	2.8416	0.2866	0.7208	0.7934
TG	0.7521	0.7361	0.7681	1.0669	2.4375	0.4773	0.7333	0.6500
TyG	0.7609	0.7452	0.7766	8.3729	2.3647	0.4404	0.7092	0.6877
TyG-BMI	0.8580	0.8461	0.8699	189.6580	2.6993	0.1844	0.6757	0.8754
TyG-WC	0.8514	0.8393	0.8635	697.6885	3.8683	0.3453	0.8142	0.7189
TyG-WHtR	0.8566	0.8447	0.8684	3.8936	2.8551	0.2393	0.7092	0.8303
TG/HDL-C ratio	0.7657	0.7503	0.7811	0.8216	2.3282	0.4163	0.6947	0.7108
HSI	0.8543	0.8421	0.8664	34.5292	3.7709	0.2989	0.7981	0.7615
VAI	0.7725	0.7574	0.7877	1.0975	2.5612	0.4343	0.7340	0.6812
LAP	0.8395	0.8270	0.8519	13.4323	2.5826	0.2280	0.6721	0.8467
ABSI	0.5880	0.5696	0.6063	0.0746	1.2682	0.6462	0.4312	0.7213
BRI	0.8385	0.8260	0.8509	2.8360	2.8416	0.2866	0.7208	0.7934
COI	0.7364	0.7205	0.7522	1.1727	1.9949	0.4534	0.6454	0.7074
Age 18-30years
BMI	0.8222	0.7488	0.8955	24.4551	3.9070	0.3590	0.8193	0.7059
WC	0.8288	0.7622	0.8954	80.3500	3.2500	0.3077	0.7647	0.7647
WHtR	0.8426	0.7797	0.9054	0.4636	3.3793	0.2333	0.7563	0.8235
TG	0.8352	0.7719	0.8985	0.7959	2.8194	0.2108	0.6975	0.8529
TyG	0.8480	0.7887	0.9073	8.1808	3.3220	0.2346	0.7521	0.8235
TyG-BMI	0.8663	0.8019	0.9307	197.9225	5.2000	0.2759	0.8529	0.7647
TyG-WC	0.8799	0.8216	0.9381	656.3063	4.1087	0.2552	0.8067	0.7941
TyG-WHtR	0.8861	0.8291	0.9430	4.0029	6.0667	0.2692	0.8739	0.7647
TG/HDL-C ratio	0.8591	0.8046	0.9136	0.6008	2.7821	0.1313	0.6723	0.9118
HSI	0.8689	0.8141	0.9237	31.6663	2.5591	0.0000	0.6092	1.0000
VAI	0.8636	0.8089	0.9182	0.9282	4.0213	0.2565	0.8025	0.7941
LAP	0.8814	0.8218	0.9409	18.9616	7.6667	0.3548	0.9118	0.6765
ABSI	0.6422	0.5513	0.7332	0.0734	1.5680	0.3717	0.4748	0.8235
BRI	0.8426	0.7797	0.9054	2.7017	3.3793	0.2333	0.7563	0.8235
COI	0.7818	0.7098	0.8537	1.1398	2.3605	0.2303	0.6387	0.8529

Abbreviations: AUC: area under the curve; other abbreviations as in Table 1.

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