Skip to main content

Table 2 Bioactive components associated to HDL

From: High density lipoproteins and oxidative stress in breast cancer

Molecule Roles
ApoA-I Structural role, lipid transport, antioxidant properties, immune response, haemostasis
Lecithin-Cholesterol Acyltransferase (LCAT) Role in HDL maturation, convertion of free cholesterol into cholesteryl ester, antioxidant properties
Paraoxonase (PON1) Antioxidant and anti-inflammatory properties of HDL, modulation of cholesterol efflux
Phospholipase A2 (PLA2)
Platelet-activating factor-acetylhydrolase (PAF-AH)
Hydrolysis of acetyl ester at the sn-2 position of PAF.
Antioxidant properties of HDL
miRNA Regulation of gene expression
Serum amyloid A (SAA) Acute-phase protein
Sphingosine-1-Phosphate
(S1P)
Signaling molecule that regulate cell growth, survival and differentiation, suppression of inflammation