From: High density lipoproteins and oxidative stress in breast cancer
Molecule | Roles |
---|---|
ApoA-I | Structural role, lipid transport, antioxidant properties, immune response, haemostasis |
Lecithin-Cholesterol Acyltransferase (LCAT) | Role in HDL maturation, convertion of free cholesterol into cholesteryl ester, antioxidant properties |
Paraoxonase (PON1) | Antioxidant and anti-inflammatory properties of HDL, modulation of cholesterol efflux |
Phospholipase A2 (PLA2) Platelet-activating factor-acetylhydrolase (PAF-AH) | Hydrolysis of acetyl ester at the sn-2 position of PAF. Antioxidant properties of HDL |
miRNA | Regulation of gene expression |
Serum amyloid A (SAA) | Acute-phase protein |
Sphingosine-1-Phosphate (S1P) | Signaling molecule that regulate cell growth, survival and differentiation, suppression of inflammation |