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Table 1 Effect of SARS-CoV-2 infection on serum lipid concentrations

From: COVID-19 and lipids. The role of lipid disorders and statin use in the prognosis of patients with SARS-CoV-2 infection

Author/ year Number of subjects Total cholesterol [mg/dl] LDL [mg/dl] HDL [mg/dl] TG [mg/dl] Conclusions
COVID-19 (+) COVID-19 (−) COVID-19 (+) COVID-19 (−) COVID-19 (+) COVID-19 (−) COVID-19 (+) COVID-19 (−)
Hu et al., [34]; 2020 114 - COVID-19 (+)80 – COVID-19 (−) 152* 188 85.4* 119 42.1* 49.5 102 187 HDL was significantly lower in severely ill group compared to moderate group. Total cholesterol, LDL, and TG were not different
Wei et al., [35]; 2020 597 - COVID-19 (+)40 - COVID-19 (−) 169* 184 88* 110 49** 52 No data No data HDL was decreased significantly in critically ill but not in severely ill patients. LDL was significantly decreased in both severely and critically ill patients
Wang et al., [36]; 2020 229 - COVID-19 (+)1140 - COVID-19 (−) 147** 181 103* 110 30.4** 53.4 95* 106 HDL were lower in severely ill patients. Total cholesterol, LDL, and triglycerides were not significantly different in severely ill patients
Wang et al., [37]; 2020 143 - COVID-19 (+) No data No data 101 No data 35.1 No data No data No data HDL were lower in severely ill patients. LDL were not significantly different in severely ill patients
Zhang et al., [38]; 2020 74 - COVID-19 (+)*** 164 No data 101 No data 40.2 No data 111 No data HDL and LDL were decreased in severely ill patients
  1. * p < 0.001; * * p < 0.05; *** patients with type 2 diabetes