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Table 1 Effect of SARS-CoV-2 infection on serum lipid concentrations

From: COVID-19 and lipids. The role of lipid disorders and statin use in the prognosis of patients with SARS-CoV-2 infection

Author/ year

Number of subjects

Total cholesterol [mg/dl]

LDL [mg/dl]

HDL [mg/dl]

TG [mg/dl]

Conclusions

COVID-19 (+)

COVID-19 (−)

COVID-19 (+)

COVID-19 (−)

COVID-19 (+)

COVID-19 (−)

COVID-19 (+)

COVID-19 (−)

Hu et al., [34]; 2020

114 - COVID-19 (+)80 – COVID-19 (−)

152*

188

85.4*

119

42.1*

49.5

102

187

HDL was significantly lower in severely ill group compared to moderate group. Total cholesterol, LDL, and TG were not different

Wei et al., [35]; 2020

597 - COVID-19 (+)40 - COVID-19 (−)

169*

184

88*

110

49**

52

No data

No data

HDL was decreased significantly in critically ill but not in severely ill patients. LDL was significantly decreased in both severely and critically ill patients

Wang et al., [36]; 2020

229 - COVID-19 (+)1140 - COVID-19 (−)

147**

181

103*

110

30.4**

53.4

95*

106

HDL were lower in severely ill patients. Total cholesterol, LDL, and triglycerides were not significantly different in severely ill patients

Wang et al., [37]; 2020

143 - COVID-19 (+)

No data

No data

101

No data

35.1

No data

No data

No data

HDL were lower in severely ill patients. LDL were not significantly different in severely ill patients

Zhang et al., [38]; 2020

74 - COVID-19 (+)***

164

No data

101

No data

40.2

No data

111

No data

HDL and LDL were decreased in severely ill patients

  1. * p < 0.001; * * p < 0.05; *** patients with type 2 diabetes