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Table 1 Distribution of demographic characteristics stratified by quartiles of baseline LDL-C in the cohort population (N = 4130)

From: Lipid biomarkers and Cancer risk - a population-based prospective cohort study in Taiwan

Variable

Total

Quartiles (mg/dL)

P value

Q1 (38–96)

Q2 (97–113)

Q3 (114–132)

Q4 (133–252)

Women (n, %)

2185 (52.9)

537 (58.8)

570 (53.8)

547 (50.1)

531 (49.9)

<.001

Age (years, %)

     

<.001

 20–64

3590 (87.0)

848 (92.9)

947 (89.4)

924 (84.6)

871 (81.9)

 

  ≥ 65

538 (13.0)

65 (7.1)

112 (10.6)

168 (15.4)

193 (18.1)

 

BMI (kg/m2, %)

     

<.001

  < 18.5

202 (5.7)

81 (10.3)

62 (6.8)

39 (4.2)

20 (2.2)

 

 18.5–23.9

1916 (53.7)

497 (63.2)

531 (58.0)

483 (51.5)

405 (43.7)

 

 24–26.9

917 (25.7)

137 (17.4)

219 (23.9)

264 (28.1)

297 (32.0)

 

  ≥ 27

532 (14.9)

71 (9.0)

104 (11.4)

152 (16.2)

205 (22.1)

 

Current smoker (n, %)

822 (19.9)

170 (18.6)

219 (20.7)

227 (20.8)

206 (19.4)

0.56

Alcohol drinking (n, %)

985 (23.9)

212 (23.2)

269 (25.4)

260 (23.8)

244 (22.9)

0.55

Betel nuts consumption (n, %)

298 (7.2)

72 (7.9)

84 (7.9)

74 (6.8)

68 (6.4)

0.42

Regular exercise (n, %)

962 (23.3)

204 (22.3)

218 (20.6)

287 (26.3)

253 (23.8)

0.015

Married (n, %)

2569 (62.2)

482 (52.8)

619 (58.5)

737 (67.5)

731 (68.7)

<.001

Education level

     

<.001

 Lower education (n, %)

2143 (51.9)

403 (44.1)

495 (46.7)

590 (54.0)

655 (61.6)

 

 Higher education (n, %)

1985 (48.1)

510 (55.9)

564 (53.3)

502 (46.0)

409 (38.4)

 

Low income level (n, %)

2940 (71.2)

674 (73.8)

739 (69.8)

760 (69.6)

767 (72.1)

0.12

Hypertension (n, %)

237 (5.7)

29 (3.2)

39 (3.7)

73 (6.7)

96 (9.0)

<.001

Diabetes mellitus (n, %)

192 (4.7)

26 (2.9)

31 (2.9)

58 (5.3)

77 (7.2)

<.001

hsCRP (mg/L)

0.24 (0.55)

0.17 (0.39)

0.21 (0.47)

0.27 (0.75)

0.27 (0.48)

<.001

Menopause (n, %)

771 (18.7)

85 (9.3)

157 (14.8)

227 (20.8)

302 (28.4)

<.001

Hormone replacement therapy (n, %)

357 (8.7)

80 (8.8)

87 (8.2)

94 (8.6)

96 (9.0)

0.93

Lipid-lowering agent use (n, %)

624 (15.1)

49 (5.4)

92 (8.7)

172 (15.8)

311 (29.2)

<.001

Lipid profile (mg/dL)

 TC (n = 4128)

 

146.0 (20.1)

171.7 (21.4)

192.3 (16.6)

230.0 (29.8)

<.001

 LDL-C (n = 4128)

 

84.6 (9.1)

105.0 (4.8)

122.3 (5.3)

153.1 (18.8)

<.001

 Triglycerides (n = 4099)

 

94.6 (69.0)

119.9 (83.3)

137.8 (82.1)

164.2 (92.5)

<.001

 Non-HDL-C (n = 4128)

 

94.3 (19.3)

116.7 (21.0)

136.2 (15.1)

171.5 (26.7)

<.001

 ∆TC (n = 3842)

 

8.7 (28.7)

1.0 (26.9)

−2.0 (29.4)

−21.9 (39.6)

<.001

 ∆LDL-C (n = 3842)

 

3.8 (24.2)

−0.7 (24.2)

−2.8 (28.0)

−18.3 (34.2)

<.001

 ∆Triglycerides (n = 3817)

 

2.8 (64.7)

−2.2 (75.3)

−1.2 (84.0)

−10.5 (86.1)

0.002

 ∆Non-HDL-C (n = 3842)

 

7.7 (26.3)

4.0 (25.3)

2.3 (29.0)

−15 (37.6)

<.001

  1. LDL-C Low density lipoprotein cholesterol, BMI Body mass index, hsCRP High-sensitivity C-reactive protein, TC Total cholesterol, Non-HDL-C Non-high-density lipoprotein cholesterol; ∆, interval change between the Taiwanese Survey on Prevalence of Hypertension, Hyperglycemia, and Hyperlipidemia in 2002 and follow-up measurement in 2007