Table 3 Subgroup analysis for the effects of interval changes in TC and LDL-C components for all-cause cancer risk during median 13.4-year follow-up

  women

1

1.07 (0.46–2.50)

0.60 (0.25–1.43)

0.74 (0.34–1.59)

0.79 (0.32–1.95)

0.66 (0.28–1.58)

  men

1

0.85 (0.43–1.69)

0.39 (0.18–0.88)

0.65 (0.36–1.18)

0.85 (0.41–1.76)

0.73 (0.35–1.48)

   < 65 years old

1

0.86 (0.46–1.59)

0.36 (0.17–0.74)

0.80 (0.46–1.42)

0.74 (0.37–1.47)

0.69 (0.37–1.30)

   ≥ 65 years old

1

1.08 (0.36–3.27)

0.84 (0.32–2.26)

0.60 (0.25–1.41)

1.24 (0.45–3.41)

0.75 (0.24–2.34)

   < 24 kg/m²

1

1.33 (0.75–2.36)

0.61 (0.32–1.14)

0.95 (0.55–1.63)

0.87 (0.44–1.73)

0.70 (0.36–1.37)

   ≥ 24 kg/m²

1

0.62 (0.27–1.40)

0.32 (0.12–0.84)

0.60 (0.32–1.14)

0.63 (0.29–1.37)

0.56 (0.26–1.21)

  women

1

0.24 (0.08–0.70)

0.42 (0.20–0.85)

0.37 (0.20–0.71)

0.76 (0.37–1.60)

0.29 (0.12–0.66)

  men

1

0.84 (0.35–2.04)

0.76 (0.38–1.52)

0.86 (0.49–1.53)

0.78 (0.33–1.82)

0.76 (0.38–1.51)

   < 65 years old

1

0.42 (0.19–0.91)

0.51 (0.29–0.89)

0.59 (0.36–0.98)

0.81 (0.42–1.54)

0.45 (0.24–0.82)

   ≥ 65 years old

1

0.74 (0.19–2.81)

0.73 (0.26–2.08)

0.69 (0.31–1.53)

1.02 (0.35–2.92)

0.64 (0.24–1.73)

   < 24 kg/m²

1

0.55 (0.27–1.12)

0.65 (0.38–1.10)

0.63 (0.39–1.02)

0.76 (0.40–1.44)

0.54 (0.29–0.98)

   ≥ 24 kg/m²

1

0.44 (0.15–1.32)

0.51 (0.23–1.12)

0.61 (0.33–1.11)

0.73 (0.33–1.62)

0.48 (0.23–1.01)