Table 4 Baseline data and comparison of the virological response rates and HBeAg serological conversion after different treatment regimens

Dyslipidemia (n, %)

5 (35.7)

32 (36.8)

31 (39.7)

0.185

0.911

Male (n, %)

12 (85.7)

73 (83.9)

58 (74.4)

2.640

0.267

Age (year)

46.3 ± 11.7

39. ± 10.1

40.4 ± 13.8

2.007

0.138

BMI (kg/m²)

23.9 ± 4.8

23.4 ± 2.8

23.4 ± 2.5

0.234

0.792

WBC (×10⁹/L)

5.6 ± 1.7

5.8 ± 1.8

6.0 ± 1.8

0.487

0.615

NE%

0.6 ± 0.1

0.6 ± 0.1

0.6 ± 0.0

0.330

0.720

NE (×10⁹/L)

3.4 ± 1.4

3.3 ± 1.4

3.5 ± 1.4

0.230

0.795

RBC (×10¹²/L)

4.8 ± 0.4

4.8 ± 0.5

4.8 ± 0.6

0.248

0.780

HB (g/L)

142.1 ± 16.3

146.1 ± 13.6

147.5 ± 16.7

0.781

0.460

RDW (%)

13.8 ± 2.1

13.6 ± 3.1

13.0 ± 0.9

1.757

0.176

PLT (×10⁹/L)

221.6 ± 97.1

216.2 ± 68.3

226.3 ± 62.6

0.444

0.642

PT (s)

14.0 ± 1.8

13.4 ± 0.9

13.4 ± 1.0

2.418

0.092

PTA (%)

89.1 ± 22.2

93.1 ± 12.1

92.6 ± 9.6

0.637

0.530

INR

1.1 ± 0.3

1.0 ± 0.1

1.0 ± 0.1

3.547

0.031

F (g/L)

3.2 ± 1.15

3.1 ± 0.8

3.0 ± 0.8

0.373

0.689

APTT (s)

37.5 ± 6.4

37.3 ± 4.2

36.6 ± 5.1

0.498

0.609

APTTR

1.1 ± 0.3

1.0 ± 0.1

1.0 ± 0.1

1.309

0.273

TT (s)

16.8 ± 1.8

17.2 ± 1.4

17.1 ± 1.4

0.477

0.621

TTR

1.0 ± 0.2

1.0 ± 0.1

1.0 ± 0.1

0.059

0.943

TB (umol/L)

58.6 ± 131.3

16.2 ± 15.6

15.1 ± 12.8

1.530

0.465

DBIL (umol/L)

46.1 ± 113.55

7.9 ± 11.8

6.9 ± 11.0

0.841

0.657

TP (g/L)

70.9 ± 8.2

74.6 ± 6.63

74.7 ± 5.9

2.263

0.107

A (g/L)

42.7 ± 7.1

44.3 ± 5.6

44.4 ± 4.9

0.621

0.539

ALT (U/L)

247.4 ± 205.0

346.9 ± 287.6

295.8 ± 193.0

1.509

0.224

AST (U/L)

228.6 ± 130.2

248.1 ± 192.7

221.9 ± 162.4

0.467

0.627

ALP (U/L)

81.4 ± 26.6

88.3 ± 21.8

85.0 ± 23.5

0.805

0.449

R-GT (U/L)

56.6 ± 37.9

78.8 ± 56.6

71.4 ± 37.4

1.492

0.228

FBG (mmol/L)

6.2 ± 2.4

5.4 ± 1.4

5.3 ± 1.3

2.699

0.070

BUN (mmol/L)

4.4 ± 1.5

4.7 ± 1.3

4.6 ± 1.1

0.358

0.699

CR (mmol/L)

62.4 ± 15.9

69.2 ± 11.2

68.3 ± 14.6

1.629

0.199

UA (umol/L)

330.7 ± 143.1

364.4 ± 98.5

377.8 ± 96.2

1.358

0.260

TC (mmol/L)

4.0 ± 1.4

4.6 ± 1.1

4.6 ± 1.2

1.826

0.164

TG (mmol/L)

1.5 ± 0.7

1.5 ± 0.7

1.5 ± 0.8

0.215

0.807

HDL-C (mmol/L)

0.9 ± 0.3

1.1 ± 0.3

1.1 ± 0.3

4.091

0.018*

LDL-C (mmol/L)

2.3 ± 1.1

2.7 ± 0.9

2.8 ± 1.0

1.759

0.175

HBsAg(S/CO)

8269.4 ± 13,647.8

5988.1 ± 9224.3

5921.1 ± 7409.6

0.434

0.649

HBeAg(S/CO)

944.3 ± 549.4

798.9 ± 455.3

832.3 ± 573.9

0.491

0.613

HBVDNA Log₁₀IU/mL

7.9 ± 0.8

7.5 ± 1.2

7.5 ± 1.1

0.625

0.537

 HBV DNA Virological Response Rate

9 (64.3)

59 (67.8)

52 (66.7)

0.076

0.963

 HBeAg serological Conversion Rate

2 (14.3)

13 (14.9)

5 (6.4)

3.147

0.207

 HBV DNA Virological Response Rate

11 (78.6)

63 (72.4)

56 (71.8)

0.276

0.871

 HBeAg serological Conversion Rate

2 (14.3)

13 (14.9)

12 (15.4)

0.014

0.993

 HBV DNA Virological Response Rate

11 (78.6)

72 (82.8)

62 (79.5)

0.343

0.843

 HBeAg serological Conversion Rate

2 (14.3)

15 (17.2)

15 (19.2)

0.243

0.886

 HBV DNA Virological Response Rate

11 (78.6)

78 (89.7)

71 (91)

1.943

0.379

 HBeAg serological Conversion Rate

3 (21.4)

22 (25.3)

27 (34.6)

2.152

0.341

 HBV DNA Virological Response Rate

13 (92.9)

82 (94.3)

72 (92.3)

0.252

0.882

 HBeAg serological Conversion Rate

4 (28.6)

29 (33.3)

34 (43.6)

2.343

0.310