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Table 2 Incidence of albuminuria using the TyG index, HOMA-IR and concordance/discordance groups

From: Discordance between the triglyceride glucose index and HOMA-IR in incident albuminuria: a cohort study from China

  

albuminuria

Cases/participants (%)

Model 1

Model 2

Model 3

OR (95% CI)

OR (95% CI)

OR (95% CI)

TyG Tertiles

 Tertile 1

44/816 (5.4%)

Reference

Reference

Reference

 Tertile 2

58/815 (7.1%)

1.28 (0.84–1.94)

1.27 (0.84–1.93)

1.17 (0.75–1.81)

 Tertile 3

101/815 (12.4%)

2.41 (1.65–3.52)

2.38 (1.63–3.47)

1.71 (1.07–2.72)

HOMA-IR Tertiles

 Tertile 1

36/815 (4.4%)

Reference

Reference

Reference

 Tertile 2

66/816 (8.1%)

1.62 (1.06–2.49)

1.65 (1.08–2.54)

1.32 (0.84–2.07)

 Tertile 3

101/815 (12.4%)

2.77 (1.86–4.12)

2.79 (1.87–4.16)

1.72 (1.07–2.78)

TyG/HOMA-IR

 TyG(−)&HOMA-IR(−)

88/1530 (5.8%)

Reference

Reference

Reference

 TyG(+)&HOMA-IR(−)

34/304 (11.2%)

2.09 (1.37–3.21)

2.06 (1.34–3.16)

1.69 (1.04–2.75)

 TyG(−)&HOMA-IR(+)

33/305 (10.8%)

1.95 (1.27–2.99)

1.93 (1.26–2.97)

1.39 (0.87–2.24)

 TyG(+)&HOMA-IR(+)

48/307 (15.6%)

3.00 (2.05–4.41)

2.98 (2.02–4.38)

1.88 (1.14–3.09)

  1. Model 1: adjusted for age and sex;
  2. Model 2: Model 1 + adjusted for current smoking, current drinking, education and physical activity;
  3. Model 3: Model 2 + adjusted for HbA1c, PP, HDL-cholesterol, LDL-cholesterol, total cholesterol, BMI and medication use of ACEIs or ARBs
  4. PP, pulse pressure; TyG, triglyceride glucose; HOMA-IR, homeostasis model assessment for insulin resistance; OR, odds ratio; CI, confidence interval; BMI, body mass index; HbA1c, glycated hemoglobin; LDL, low density lipoprotein; HDL, high density lipoprotein; ACEIs, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers
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Lipids in Health and Disease

ISSN: 1476-511X