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Table 3 Plasma levels of TC, TG, LDL-C, and HDL-C of the rabbits

From: CRISPR/Cas9-mediated knockout of APOC3 stabilizes plasma lipids and inhibits atherosclerosis in rabbits

Diet

Group

TC (mg/dl)

TG (mg/dl)

LDL-C (mg/dl)

HDL-C (mg/dl)

NC

WT (n = 5)

48.0 ± 8.1

59.9 ± 13.2

23.7 ± 2.9

28.7 ± 4.4

AC1♂

44.6 ± 7.5

23.8 ± 11.8

18.4 ± 2.7

31.1 ± 5.1

AC2♀

30.8 ± 6.9

36.3 ± 8.7

18.6 ± 3.1

21.5 ± 6.3

AC3♀

54.3 ± 8.8

30.5 ± 6.5

20.3 ± 2.6

33.7 ± 3.8

HF (6 W)

WT (n = 5)

786.6 ± 48.5

877.4 ± 69.8

329.9 ± 23.3

26.4 ± 9.6

AC1♂

288.5

256.0

125.3

43.8

AC2♀

318.8

285.7

159.3

45.1

AC3♀

355.3

298.5

201.2

39.2

HF (12 W)

WT (n = 5)

805.3 ± 39.7

890.7 ± 46.9

403.1 ± 49.3

25.1 ± 3.8

AC1♂

316.6

224.5

221.4

37.6

AC2♀

436.1

297.1

226.0

40.3

AC3♀

399.0

308.3

239.5

38.5