Race and sex differences in HDL peroxide content among American adults with and without type 2 diabetes

Table 1 Demographic and biomarker variables for MIDUS participants stratified by race

	White 80.6% N = 1533	African American 19.4% N = 370	X²
Demographic Variables
Sex^a
Male	48.5% (743)	31.6% (117)	<.001
Female	51.5% (790)	68.4% (253)	<.001
Age^b
< 50	42.03 ± 5.48 (468)	41.45 ± 5.96 (163)	<.001
≥ 50	63.26 ± 8.7 (1065)	59.24 ± 7.18 (207)	<.001
Health and Biomarker Variables
Adiposity and Glucoregulation^c
BMI (kg/m²)	29.12 ± 6.16	33.02 ± 8.57	<.001
Waist circumference (cm)	96.88 ± 17.43	101.66 ± 18.43	<.001
HbA1c (%)	5.81 ± 0.85	6.41 ± 1.74	<.001
HOMA-IR	3.79 ± 5.80	5.22 ± 5.48	<.001
Blood Lipid Values^d
Total Cholesterol (mg/dL)	184.5 ± 38.3	182.7 ± 43.3	0.231
Triglycerides (mg/dL)	125.19 ± 71.54	110.64 ± 68.62	<.001
LDL-C (mg/dL)	102.48 ± 34.21	100.80 ± 37.78	0.187
Non-HDL-C (mg/dL)	127.9 ± 38.7	123.3 ± 43.0	0.010
HDL-C (mg/dL)	56.62 ± 18.78	59.42 ± 18.91	0.004
HDLperox	11.81 ± 5.66	10.3 ± 4.7	<.001

^a A higher percent of both White and Afr-Amer participants were female. ^b Although the age distribution was similar across race, more of the older participants were White. ^cAfr-Amers were more likely to be overweight with more insulin resistance indicative of poor glucoregulation. ^d Afr-Amer tended to have more HDL-C. Even when HDL concentrations were controlled in the assay, the Afr-Amer particiants had significantly lower HDLperox levels

ISSN: 1476-511X