Table 2 Baseline characteristics of different groups according to NFS status

 Age (years)

55.5 ± 10.9

49.2 ± 10.1

58.7 ± 8.9

66.8 ± 8.7

<  0.0001

 Male sex, n(%)

1215 (60.6)

506 (63.4)

636 (59.3)

73 (52.9)

0.034

 BMI (kg/m²)

25.7 ± 3.4

25 ± 3.2

26 ± 3.3

26.6 ± 4.1

<  0.0001

 CAD, n(%)

1179 (58.7)

401 (50.3)

681 (63.5)

97 (70.3)

<  0.0001

 DM, n(%)

471 (23.5)

93 (11.7)

327 (30.5)

51 (37.0)

<  0.0001

 Hypertension, n(%)

1229 (61.2)

426 (53.4)

703 (65.6)

100 (72.5)

<  0.0001

 Family history of CAD, n(%)

440 (21.9)

195 (24.4)

235 (21.9)

10 (7.2)

<  0.0001

 Smoking, n(%)

683 (34.0)

303 (38.0)

351 (32.7)

29 (21.0)

<  0.0001

 Drinking, n(%)

417 (20.8)

185 (23.2)

210 (19.6)

22 (15.9)

0.058

 SBP (mmHg)

127.6 ± 18.5

125.2 ± 18

128.7 ± 18.7

132.7 ± 18.5

<  0.0001

 DBP (mmHg)

79.5 ± 11.2

79.9 ± 11.7

79.4 ± 10.9

77.8 ± 10.4

0.117

 Platelet (10⁹/L)

216.0 ± 53.6

247.36 ± 52.84

200.11 ± 40.91

157.41 ± 40.38

<  0.0001

 ALT (IU/L)

20 (14,28)

22 (16,32)

19 (14,27.75)

14 (10,20)

<  0.0001

 AST (IU/L)

18 (15,22)

18 (15,22)

18 (15,21)

18.5 (15,24)

0.375

 GGT (IU/L)

25 (18,39)

26.5 (18,43)

24 (18,37)

22 (16,33)

<  0.0001

 ALB (g/L)

42.5 ± 4.3

44.0 ± 4.4

41.9 ± 3.8

39.0 ± 4.1

<  0.0001

 TC (mmol/L)

4.8 ± 1.01

4.90 ± 1.08

4.90 ± 0.95

4.60 ± 0.96

0.021

 TG (mmol/L)

1.6 (1.15,2.31)

1.61 (1.15,2.38)

1.62 (1.18,2.31)

1.42 (1.06,1.98)

0.018

 HDL-C (mmol/L)

1.11 ± 0.39

1.10 ± 0.43

1.12 ± 0.37

1.06 ± 0.30

0.109

 LDL-C (mmol/L)

3.13 ± 0.91

3.14 ± 1.00

3.14 ± 0.85

2.98 ± 0.79

0.079

 Glucose (mmol/L)

5.66 ± 1.96

5.00 ± 1.26

5.91 ± 2.36

5.73 ± 1.57

<  0.0001

 HbA1C (%)

6.05 ± 1.88

5.75 ± 2.02

6.24 ± 1.82

6.31 ± 0.92

<  0.0001

 PCSK9(ng/mL)

228.56 (190.57,272.29)

224.72 (184.54,265.17)

230.13 (193.44,275.58)

244.28 (194.15,284.31)

0.005

 Antiplatelet drugs, n(%)

595 (29.6)

189 (23.7)

361 (33.7)

45 (32.6)

<  0.0001

 Antihypertensive drugs, n(%)

694 (34.6)

222 (27.8)

414 (38.6)

58 (42.0)

<  0.0001