Table 1 Characteristics of type 2 diabetes patients with hypertriglyceridemia
Variables | Total | With statins | Without statins | P* |
|---|---|---|---|---|
Number (%) | 110 | 47 | 63 | |
Age, mean ± SD, years | 62.5 ± 12.6 | 66.6 ± 9.8 | 59.4 ± 13.6 | 0.0027 |
Men: Women | 70: 40 | 26: 21 | 44: 19 | 0.1173 |
BMI, mean ± SD, kg/m2 | 26.7 ± 3.9 | 26.8 ± 4.3 | 26.6 ± 3.6 | 0.7968 |
HbA1c, mean ± SD, % | 7.3 ± 1.4 | 7.4 ± 1.4 | 7.2 ± 1.5 | 0.6683 |
eGFR, mean ± SD, mL /min/1.73 m2 | 72.4 ± 18.8 | 66.6 ± 13.4 | 76.7 ± 21.1 | 0.0051 |
Complications | ||||
Hypertension, no. (%) | 74 (67.3) | 34 (72.3) | 40 (63.5) | 0.3279 |
CVD/stroke, no. (%) | 21 (19.1) | 9 (19.2) | 12 (19.1) | 0.9893 |
Treatment for diabetes | ||||
OHA, no. (%) | 60 (54.5) | 30 (63.8) | 30 (47.6) | 0.2835 |
Insulin + OHA, no. (%) | 16 (14.5) | 7 (15.0) | 9 (14.3) | |
Insulin, no (%) | 4 (3.6) | 1 (2.1) | 3 (4.8) | |
TG, median (IQR), mmol/L | 3.1 (2.4-4.2) | 2.9 (2.2-3.5) | 3.3 (2.5-5.3) | 0.0167 |
LDL-C, mean ± SD, mmol/L | 2.9 ± 0.9 | 2.9 ± 0.7 | 2.9 ± 1.0 | 0.9221 |
HDL-C, mean ± SD, mmol/L | 1.2 ± 0.3 | 1.3 ± 0.3 | 1.2 ± 0.3 | 0.0150 |
Non − HDL-C, mean ± SD, mmol/L | 4.6 ± 1.0 | 4.3 ± 0.8 | 4.8 ± 1.1 | 0.0122 |
TG/LDL-C ratio, median (IQR) | 1.0 (0.8-1.7) | 0.9 (0.7-1.3) | 1.1 (0.8-2.2) | 0.0803 |
TG/HDL-C ratio, median (IQR) | 2.5 (1.8-3.0) | 2.3 (1.5-3.1) | 2.7 (1.9-5.4) | 0.0169 |
LDL-C/HDL-C ratio, mean ± SD | 2.5 ± 0.9 | 2.3 ± 0.8 | 2.6 ± 0.9 | 0.1050 |
Non − HDL-C/HDL-C ratio, mean ± SD | 4.1 ± 1.8 | 3.5 ± 1.3 | 4.5 ± 2.0 | 0.0039 |
Lipoprotein fraction (PAG electrophoresis) | ||||
HDL, mean ± SD, % | 20.7 ± 5.6 | 21.4 ± 4.5 | 20.2 ± 6.4 | 0.2620 |
LDL, mean ± SD, % | 39.7 ± 12.7 | 41.7 ± 10.0 | 38.2 ± 14.3 | 0.1544 |
Midband, mean ± SD, % | 17.6 ± 8.5 | 17.7 ± 7.8 | 17.5 ± 9.0 | 0.9419 |
VLDL, mean ± SD, % | 20.1 ± 8.4 | 19.1 ± 6.5 | 24.1 ± 9.1 | 0.0023 |
LDL-MI, median (IQR) | 0.393 (0.353-0.420) | 0.381 (0.350-0.404) | 0.398 (0.355-0.426) | 0.0781 |