Table 3 Comparison of AUC, sensitivity, and specificity for each marker in predicting higher LDL-MI
Variables | AUC (95% CI) | Sensitivity | Specificity | Cut-off point |
|---|---|---|---|---|
Total (n = 110) | ||||
TG | 0.854 (0.783-0.926) | 79.5% | 72.7% | 3.1 mmol/L |
LDL-Ca | 0.658 (0.543-0.773) | 61.4% | 71.2% | 2.8 mmol/L |
Non − HDL-C | 0.643 (0.528-0.758) | 52.3% | 81.8% | 4.9 mmol/L |
LDL fraction (PAG)a | 0.766 (0.679-0.854) | 70.5% | 66.7% | 41% |
Midband fraction (PAG) | 0.738 (0.644-0.832) | 75.0% | 65.2% | 17% |
TG/LDL-C ratio | 0.865 (0.786-0.945) | 86.4% | 86.4% | 1.1 |
TG/HDL-C ratio | 0.844 (0.772-0.917) | 75.0% | 75.8% | 2.6 |
LDL-C/HDL-C ratio | 0.516 (0.398-0.635) | 47.7% | 62.1% | 2.2 |
Non − HDL-C/HDL-C ratio | 0.717 (0.615-0.818) | 68.2% | 68.2% | 3.8 |
With statins (n = 47) | ||||
TG | 0.755 (0.604-0.907) | 71.4% | 72.7% | 3.1 mmol/L |
LDL-Ca | 0.466 (0.262-0.671) | 57.1% | 57.6% | 2.8 mmol/L |
Non − HDL-C | 0.682 (0.500-0.863) | 64.3% | 69.7% | 4.5 mmol/L |
LDL fraction (PAG)a | 0.656 (0.491-0.821) | 64.3% | 66.7% | 41% |
Midband fraction (PAG) | 0.824 (0.695-0.952) | 78.6% | 75.8% | 21% |
TG/LDL-C ratio | 0.697 (0.507-0.887) | 78.6% | 78.3% | 1.1 |
TG/HDL-C ratio | 0.747 (0.602-0.892) | 78.6% | 63.6% | 2.3 |
LDL-C/HDL-C ratio | 0.623 (0.448-0.799) | 64.3% | 63.6% | 2.4 |
Non − HDL-C/HDL-C ratio | 0.691 (0.527-0.854) | 64.3% | 69.7% | 3.5 |
Without statins (n = 63) | ||||
TG | 0.910 (0.839-0.981) | 80.0% | 87.9% | 3.3 mmol/L |
LDL-Ca | 0.760 (0.630-0.889) | 63.3% | 90.9% | 2.6 mmol/L |
Non − HDL-C | 0.614 (0.463-0.765) | 56.7% | 78.8% | 5.0 mmol/L |
LDL fraction (PAG)a | 0.838 (0.735-0.929) | 63.3% | 90.9% | 35% |
Midband fraction (PAG) | 0.701 (0.571-0.831) | 70.0% | 69.7% | 17% |
TG/LDL-C ratio | 0.945 (0.884-1.000) | 90.0% | 93.9% | 1.1 |
TG/HDL-C ratio | 0.892 (0.815-0.969) | 80.0% | 78.8% | 2.7 |
LDL-C/HDL-C ratio | 0.591 (0.435-0.747) | 53.3% | 81.8% | 2.2 |
Non − HDL-C/HDL-C ratio | 0.724 (0.590-0.859) | 66.7% | 81.8% | 4.3 |