Characteristics and clinical significance of lipid metabolism in patients with gastrointestinal stromal tumor

Table 2 the relation between pathological significance and blood lipids in GISTs(X ± s)

	n	TG	P	LDL-C	P	HDL-C	P	CHOL	P	TG/HDL-C	P
	n	(mmol/L)		(mmol/L)		(mmol/L)		(mmol/L)
CD117
Positive	665	1.32 ± 0.96	0.860	2.49 ± 0.78	0.810	1.16 ± 0.34	0.336	4.18 ± 0.99	0.804	1.31 ± 1.31	0.991
Negative	9	1.27 ± 0.46		2.43 ± 0.59		1.05 ± 0.35		4.09 ± 0.92		1.31 ± 0.77
CD34
Positive	574	1.31 ± 0.91	0.555	2.54 ± 0.78	0.000	1.19 ± 0.34	0.000	4.24 ± 0.99	0.000	1.26 ± 1.14	0.010
Negative	98	1.38 ± 1.19		2.24 ± 0.70		1.02 ± 0.33		3.83 ± 0.96		1.62 ± 1.99
DOG-1
Positive	663	1.31 ± 0.85	0.000	2.49 ± 0.78	0.758	1.17 ± 0.34	0.125	4.18 ± 0.99	0.985	1.29 ± 1.22	0.001
Negative	9	2.47 ± 3.94		2.42 ± 0.69		0.99 ± 0.34		4.17 ± 0.91		2.77 ± 4.31
SMA
Positive	231	1.41 ± 1.24	0.089	2.44 ± 0.79	0.173	1.13 ± 0.34	0.147	4.11 ± 1.02	0.198	1.42 ± 1.65	0.127
Negative	441	1.28 ± 0.76		2.52 ± 0.77		1.17 ± 0.34		4.21 ± 0.99		1.26 ± 1.09
S-100
Positive	16	1.32 ± 0.71	0.978	2.46 ± 0.93	0.862	0.98 ± 0.33	0.031	3.96 ± 1.18	0.372	1.66 ± 1.34	0.28
Negative	657	1.32 ± 0.96		2.49 ± 0.77		1.17 ± 0.34		4.18 ± 0.99		1.30 ± 1.31
Ki67%
< 5%	395	1.34 ± 1.08	0.583	2.47 ± 0.74	0.409	1.18 ± 0.34	0.081	4.18 ± 0.92	0.886	1.32 ± 1.46	0.875
≥ 5%	269	1.30 ± 0.75		2.53 ± 0.82		1.13 ± 0.34		4.17 ± 1.09		1.30 ± 1.06
Rank of risk^a
Extremely low risk	117	1.34 ± 0.83	0.012	2.62 ± 0.80	0.033	1.27 ± 0.36	0.000	4.44 ± 0.95	0.000	1.24 ± 1.21	0.169
Low risk	224	1.48 ± 1.27		2.47 ± 0.75		1.17 ± 0.34		4.19 ± 0.97		1.46 ± 1.56
Medium risk	70	1.28 ± 0.60		2.64 ± 0.80		1.20 ± 0.32		4.38 ± 1.07		1.17 ± 0.69
High risk	283	1.20 ± 0.75		2.41 ± 0.79		1.11 ± 0.33		4.01 ± 0.99		1.24 ± 1.21

^a Extremely low risk was defined as a GIST with tumor size ≤2 cm and arbitrary mitotic index, or 2 cm < tumor size ≤5 cm and mitotic index < 5 per 50 HPF. low risk was defined as a GIST with 5 cm < tumor size ≤10 cm and mitotic index < 5 per 50 HPF. Medium risk was defined as a GIST with tumor size > 10 cm and mitotic index < 5 per 50 HPF, or 2 cm < tumor size ≤5 cm and mitotic index ≥5 per 50 HPF. High risk was defined as a GIST with tumor size > 5 cm and mitotic index ≥5 per 50 HPF

ISSN: 1476-511X