Higher fasting triglyceride predicts higher risks of diabetes mortality in US adults

Table 2 Association of triglyceride (independent variable) ^a with diabetes markers (dependent variables) ^a in 26,582 adults

	Model 1		Model 2		Model 3		Model 4
	β	P value	β	P value	β	P value	β	P value
All participants (N = 26,582)
Plasma glucose	0.275	< 0.001	0.226	< 0.001	0.193	< 0.001	0.114	< 0.001
Blood HbA_1c	0.223	< 0.001	0.192	< 0.001	0.159	< 0.001	0.074	< 0.001
Serum insulin	0.367	< 0.001	0.395	< 0.001	0.268	< 0.001	0.258	< 0.001
HOMA-IR	0.401	< 0.001	0.411	< 0.001	0.290	< 0.001	0.259	< 0.001
Participants without diabetes (N = 22,909)
Plasma glucose	0.200	< 0.001	0.119	< 0.001	0.077	< 0.001	0.074	< 0.001
Blood HbA_1c	0.119	< 0.001	0.086	< 0.001	0.050	< 0.001	0.035	< 0.001
Serum insulin	0.358	< 0.001	0.393	< 0.001	0.267	< 0.001	0.268	< 0.001
HOMA-IR	0.366	< 0.001	0.386	< 0.001	0.262	< 0.001	0.261	< 0.001
Participants with diabetes (N = 3673)
Plasma glucose	0.286	< 0.001	0.284	< 0.001	0.288	< 0.001	0.292	< 0.001
Blood HbA_1c	0.200	< 0.001	0.215	< 0.001	0.213	< 0.001	0.204	< 0.001
Serum insulin	0.250	< 0.001	0.250	< 0.001	0.209	< 0.001	0.216	< 0.001
HOMA-IR	0.342	< 0.001	0.341	< 0.001	0.306	< 0.001	0.315	< 0.001

Abbreviations: HbA_1c glycated hemoglobin, HOMA-IR homeostatic model assessment for insulin resistance
^aTriglyceride, plasma glucose, blood HbA_1c, serum insulin, and HOMA-IR, were natural log-transformed. Model 1: unadjusted; Model 2: adjusted for age, sex, and ethnicity; Model 3: adjusted for all the factors in Model 2 plus obesity, poverty-income ratio, education, physical activity, alcohol consumption, smoking status, and survey period; Model 4: adjusted for all the factors in Model 3 plus hypercholesterolemia, hypertension, diabetes, and family history of diabetes

ISSN: 1476-511X