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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Adipocyte-specific deletion of PIP5K1c reduces diet-induced obesity and insulin resistance by increasing energy expenditure

Fig. 2

PIP5K1c KO mice are resistant to HFD induced obesity. (a-c) Growth curves a, body weight gain b and body shape c of HFD-fed WT or KO mice. d eWAT mass of WT and KO mice after 16 weeks HFD feeding, N = 8–9/group. e subWAT mass of WT and KO mice after 16 weeks HFD feeding, N = 8–9/group. f BAT mass of WT and KO mice after 16 weeks HFD feeding, N = 8–9/group. g Lean mass of WT and KO mice after 16 weeks HFD feeding, N = 6. h Representative pictures of different adipose tissue from WT and KO mice after 16 weeks HFD feeding. i H&E staining of different adipose tissues in WT and KO mice after 16 weeks HFD feeding. j Adipocyte average size in eWAT of HFD-fed WT and KO mice, N = 5/group. k Adipocyte average size in subWAT of HFD-fed WT and KO mice, N = 5/group. *P < 0.05; **P < 0.01

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