From: High remnant cholesterol level is relevant to diabetic retinopathy in type 2 diabetes mellitus
Variables | All (n = 456) | Non-DR (n = 239) | DR (n = 217) | P-value |
---|---|---|---|---|
Age (years) | 53.54 ± 12.13 / 55 (44–63) | 53 (40–62) | 57 (47–64) | 0.009** |
Male gender, n (%) | 292 (64) | 161 (65.2) | 131 (62.7) | 0.579 |
Diabetes duration (years) | 9.73 ± 6.97 / 9 (4–15) | 7 (3–12) | 11 (6–16) | 0.001** |
Hypertension, n (%) | 232 (46.4) | 105 (42.5) | 127 (50.2) | 0.085 |
Current smoking, n (%) | 150 (32.9) | 89 (36) | 61 (29.2) | 0.121 |
DNP, n (%) | 175 (38.5) | 79 (33.2) | 96 (44.2) | 0.027 |
BMI (kg/m2) | 25.6 (23.92–27.95) | 25.39 (23.84–27.39) | 25.6 (23.98–28.09) | 0.929 |
SBP (mmHg) | 140 (126–150) | 137 (123–150) | 140 (130–154) | 0.007* |
DBP (mmHg) | 80 (74–90) | 80 (72–88) | 81 (75–90) | 0.067 |
FBG (mmol/L) | 8.44 (6.88–10.61) | 8.2 (6.79–10.54) | 8.59 (7.04–10.71) | 0.163 |
HbA1c (%) | 8.4 (7.2–9.6) | 8.2 (7.1–9.5) | 8.5 (7.6–9.8) | 0.076 |
HbA1c (mmol/mol) | 68 (55–81) | 66 (54–80) | 69 (60–84) | 0.057 |
Fasting C-Peptide (ng/ml) | 1.5 (1.0–2.2) | 1.55 (1.0–2.3) | 1.5 (1.0–2.15) | 0.426 |
Neutrophil (× 109/L) | 3.71 (3.05–4.45) | 3.48 (2.96–4.41) | 3.85 (3.17–4.5) | 0.01* |
Lymphocyte (×109/L) | 2.22 (1.78–2.64) | 2.26 (1.87–2.69) | 2.17 (1.73–2.56) | 0.053 |
Monocyte (×109/L) | 0.38 (0.31–0.45) | 0.38 (0.3–0.45) | 0.38 (0.31–0.44) | 0.31 |
TC (mmol/L) | 5.02 (4.42–5.74) | 4.96 (4.24–5.58) | 5.13 (4.58–5.96) | 0.000** |
TG (mmol/L) | 2.18 (1.4–3.43) | 2.12 (1.43–3.2) | 2.31 (1.35–3.59) | 0.286 |
HDL-C (mmol/L) | 1.15 (0.99–1.3) | 1.11 (0.99–1.28) | 1.16 (1.00–1.325) | 0.496 |
LDL-C (mmol/L) | 3.09 (2.66–3.58) | 3.14 (2.65–3.59) | 3.05 (2.66–3.55) | 0.822 |
APOA (g/L) | 1.26 (1.13–1.39) | 1.25 (1.14–1.39) | 1.21 (1.11–1.40) | 0.981 |
APOB (g/L) | 1.03 (0.87–1.21) | 1.035 (0.84–1.2) | 1.03 (0.9–1.22) | 0.2 |
RC (mmol/L) | 0.65 (0.45–0.99) | 0.54 (0.31–0.83) | 0.74 (0.60–1.12) | 0.000** |
TyG-index | 9.62 ± 0.78 | 9.52 ± 0.73 | 9.72 ± 0.82 | 0.006* |
NLR | 1.64 (1.36–2.03) | 1.60 (1.30–1.93) | 1.69 (1.41–2.26) | 0.000** |
Uric Acid (μmol/L) | 329.3 (280.4–393.8) | 326.3 (276.6–395) | 330.8 (286.05–393.7) | 0.644 |
Creatinine (μmol/L) | 61.3 (50.6–70.5) | 60.5 (50.45–70.13) | 62.3 (51.1–72.4) | 0.384 |
eGFR (ml/min/1.73m2) | 108.6 (97.68–121.03) | 110.96 (98.24–123.10) | 106.27 (96–117.95) | 0.013 |
mAlb (mg/24 h) | 20.31 (19.76–33.63) | 19.95 (19.57–23.56) | 20.71 (19.95–56.53) | 0.000** |
Metformin, n (%) | 277 (60.7) | 149 (60.3) | 128 (61.2) | 0.841 |
DPP-IV inhibitor, n (%) | 189 (41.4) | 98 (39.7) | 91 (43.5) | 0.404 |
Acarbose, n (%) | 68 (15.3) | 38 (15.9) | 30 (14.6) | 0.712 |
Insulin, n (%) | 139 (30.5) | 72 (29.1) | 67 (32.1) | 0.502 |
Anitihypertensive drugs, n (%) | 159 (34.9) | 76 (30.8) | 83 (39.7) | 0.046* |