Table 2 Association of dietary fat and fatty acids intake with risk of ESCC
Dietary items | N (controls/cases) | Crude OR (95% CI) * | Adjusted OR (95% CI) *†| Adjusted OR (95% CI) *‡ |
|---|---|---|---|---|
Dietary fat | ||||
 Quintile 1 (≤43.81 μg/day) | 180/175 | 1.00 | 1.00 | 1.00 |
 Quintile 2 (> 43.81 ~ ≤ 55.64 μg/day) | 173/181 | 1.08 (0.80, 1.45) | 0.97 (0.70, 1.33) | 0.91 (0.65, 1.29) |
 Quintile 3 (> 55.64 ~ ≤ 65.04 μg/day) | 196/158 | 0.83 (0.62, 1.11) | 0.76 (0.55, 1.06) | 0.71 (0.50, 1.01) |
 Quintile 4 (> 65.04 ~ ≤ 79.11 μg/day) | 188/166 | 0.91 (0.68, 1.22) | 0.79 (0.56, 1.11) | 0.77 (0.53, 1.12) |
 Quintile 5 (> 79.11 μg/day) | 155/199 | 1.32 (0.98, 1.78) | 1.16 (0.80, 1.67) | 1.28 (0.80, 2.05) |
 P for trend | 0.2534 | 0.254 | 0.896 | 0.986 |
 Every 10-unit increment |  | 1.07 (1.03, 1.11) | 1.05 (1.00, 1.11) | 1.11 (1.04, 1.19) |
Total fatty acid | ||||
 Quintile 1 (≤40.93 μg/day) | 161/195 | 1.00 | 1.00 | 1.00 |
 Quintile 2 (> 40.93 ~ ≤ 52.01 μg/day) | 157/195 | 1.03 (0.76, 1.38) | 0.90 (0.65, 1.25) | 0.81 (0.58, 1.15) |
 Quintile 3 (> 52.01 ~ ≤ 60.91 μg/day) | 195/159 | 0.67 (0.50, 0.90) | 0.56 (0.40, 0.77) | 0.48 (0.34, 0.69) |
 Quintile 4 (> 60.91 ~ ≤ 74.48 μg/day) | 196/158 | 0.67 (0.49, 0.89) | 0.53 (0.37, 0.74) | 0.42 (0.29, 0.62) |
 Quintile 5 (> 74.48 μg/day) | 183/172 | 0.78 (0.58, 1.04) | 0.54 (0.38, 0.78) | 0.44 (0.28, 0.70) |
 P for trend | 0.0053 | 0.005 | 0 | 0 |
 Every 10-unit increment |  | 1.00 (0.96, 1.04) | 0.95 (0.91, 1.00) | 0.93 (0.87, 1.00) |
Saturated fatty acid | ||||
 Quintile 1 (≤11.99 μg/day) | 177/178 | 1.00 | 1.00 | 1.00 |
 Quintile 2 (> 11.99 ~ ≤ 15.94 μg/day) | 175/179 | 1.02 (0.76, 1.37) | 0.94 (0.68, 1.29) | 0.88 (0.62, 1.23) |
 Quintile 3 (> 15.94 ~ ≤ 18.6 μg/day) | 187/167 | 0.89 (0.66, 1.19) | 0.84 (0.61, 1.17) | 0.76 (0.53, 1.08) |
 Quintile 4 (> 18.6 ~ ≤ 22.92 μg/day) | 189/165 | 0.87 (0.65, 1.17) | 0.70 (0.50, 0.98) | 0.64 (0.44, 0.92) |
 Quintile 5 (> 22.92 μg/day) | 164/190 | 1.15 (0.86, 1.55) | 0.97 (0.67, 1.39) | 0.93 (0.59, 1.47) |
 P for trend | 0.7119 | 0.712 | 0.348 | 0.161 |
 Every 10-unit increment |  | 1.20 (1.06, 1.37) | 1.14 (0.97, 1.34) | 1.21 (0.96, 1.51) |
Monounsaturated fatty acids | ||||
 Quintile 1 (≤19.48 μg/day) | 158/198 | 1.00 | 1.00 | 1.00 |
 Quintile 2 (> 19.48 ~ ≤ 25 μg/day) | 144/209 | 1.16 (0.86, 1.56) | 1.05 (0.76, 1.45) | 0.94 (0.66, 1.33) |
 Quintile 3 (> 25 ~ ≤ 29.25 μg/day) | 192/161 | 0.67 (0.50, 0.90) | 0.53 (0.38, 0.73) | 0.43 (0.30, 0.62) |
 Quintile 4 (> 29.25 ~ ≤ 35.25 μg/day) | 208/147 | 0.56 (0.42, 0.76) | 0.43 (0.31, 0.61) | 0.33 (0.22, 0.47) |
 Quintile 5 (> 35.25 μg/day) | 190/164 | 0.69 (0.51, 0.93) | 0.45 (0.31, 0.65) | 0.33 (0.21, 0.51) |
 P for trend |  | <  0.001 | <  0.001 | <  0.001 |
 Every 10-unit increment |  | 0.92 (0.84, 1.00) | 0.81 (0.72, 0.91) | 0.70 (0.59, 0.81) |
Polyunsaturated fatty acid | ||||
 Quintile 1 (≤8.88 μg/day) | 148/207 | 1.00 | 1.00 | 1.00 |
 Quintile 2 (> 8.88 ~ ≤ 10.85 μg/day) | 166/188 | 0.81 (0.60, 1.09) | 0.73 (0.53, 1.01) | 0.66 (0.47, 0.93) |
 Quintile 3 (> 10.85 ~ ≤ 13.22 μg/day) | 205/148 | 0.52 (0.38, 0.70) | 0.41 (0.29, 0.57) | 0.36 (0.24, 0.51) |
 Quintile 4 (> 13.22 ~ ≤ 16.55 μg/day) | 178/176 | 0.71 (0.53, 0.95) | 0.54 (0.38, 0.77) | 0.49 (0.33, 0.73) |
 Quintile 5 (> 16.55 μg/day) | 195/160 | 0.59 (0.44, 0.79) | 0.38 (0.26, 0.56) | 0.32 (0.20, 0.51) |
 P for trend |  | <  0.001 | <  0.001 | <  0.001 |
 Every 10-unit increment |  | 0.93 (0.80, 1.08) | 0.80 (0.66, 0.96) | 0.85 (0.66, 1.10) |