Table 5 Stratified analysis by alcohol drinking on the association of dietary fat and fatty acids intake with the risk of ESCC

 Quintile 1 (≤43.81 μg/day)

121/78

1.00

1.00

1.00

1.00

 Quintile 2 (> 43.81 ~ ≤ 55.64 μg/day)

81/68

1.30 (0.85, 2.00)

1.16 (0.72, 1.87)

0.75 (0.49, 1.14)

0.69 (0.42, 1.14)

 Quintile 3 (> 55.64 ~ ≤ 65.04 μg/day)

100/55

0.85 (0.55, 1.32)

0.78 (0.47, 1.30)

0.65 (0.42, 1.00)

0.60 (0.36, 1.00)

 Quintile 4 (> 65.04 ~ ≤ 79.11 μg/day)

96/60

0.97 (0.63, 1.49)

0.69 (0.40, 1.19)

0.70 (0.46, 1.07)

0.62 (0.35, 1.07)

 Quintile 5 (> 79.11 μg/day)

78/55

1.09 (0.70, 1.71)

0.57 (0.27, 1.18)

1.14 (0.74, 1.74)

1.69 (0.86, 3.33)

 P for trend

0.834

0.053

0.45

0.41

 Every 10-unit increment

1.04 (0.98, 1.10)

0.91 (0.81, 1.02)

1.06 (1.01, 1.12)

1.19 (1.08, 1.31)

 Quintile 1 (≤40.93 μg/day)

111/86

1.00

1.00

1.00

1.00

 Quintile 2 (> 40.93 ~ ≤ 52.01 μg/day)

73/72

1.27 (0.83, 1.96)

0.96 (0.59, 1.56)

0.67 (0.43, 1.03)

0.59 (0.35, 0.98)

 Quintile 3 (> 52.01 ~ ≤ 60.91 μg/day)

101/54

0.69 (0.45, 1.06)

0.50 (0.30, 0.83)

0.51 (0.33, 0.79)

0.39 (0.23, 0.65)

 Quintile 4 (> 60.91 ~ ≤ 74.48 μg/day)

101/57

0.73 (0.47, 1.12)

0.35 (0.20, 0.61)

0.49 (0.31, 0.75)

0.31 (0.17, 0.54)

 Quintile 5 (> 74.48 μg/day)

90/47

0.67 (0.43, 1.06)

0.16 (0.07, 0.35)

0.62 (0.40, 0.94)

0.49 (0.25, 0.94)

 P for trend

0.0108

0.011

< 0.001

0.017

0.004

 Every 10-unit increment

0.98 (0.92, 1.04)

0.71 (0.62, 0.81)

0.99 (0.94, 1.05)

0.98 (0.89, 1.09)

 Quintile 1 (≤11.99 μg/day)

120/79

1.00

1.00

1.00

1.00

 Quintile 2 (> 11.99 ~ ≤ 15.94 μg/day)

77/72

1.42 (0.93, 2.18)

1.17 (0.73, 1.88)

0.63 (0.41, 0.96)

0.60 (0.36, 0.99)

 Quintile 3 (> 15.94 ~ ≤ 18.6 μg/day)

99/57

0.87 (0.57, 1.35)

0.75 (0.45, 1.24)

0.72 (0.47, 1.10)

0.63 (0.37, 1.06)

 Quintile 4 (> 18.6 ~ ≤ 22.92 μg/day)

101/57

0.86 (0.56, 1.32)

0.53 (0.31, 0.89)

0.71 (0.46, 1.09)

0.54 (0.31, 0.93)

 Quintile 5 (> 22.92 μg/day)

79/51

0.98 (0.62, 1.54)

0.39 (0.19, 0.81)

0.94 (0.62, 1.44)

1.08 (0.56, 2.08)

 P for trend

0.319

0.002

0.712

0.961

 Every 10-unit increment

1.10 (0.91, 1.33)

0.56 (0.37, 0.83)

1.19 (1.00, 1.42)

1.07 (0.96, 2.01)

 Quintile 1 (≤19.48 μg/day)

107/90

1.00

1.00

1.00

1.00

 Quintile 2 (> 19.48 ~ ≤ 25 μg/day)

72/77

1.27 (0.83, 1.95)

0.88 (0.54, 1.43)

0.87 (0.56, 1.34)

0.77 (0.46, 1.29)

 Quintile 3 (> 25 ~ ≤ 29.25 μg/day)

93/53

0.68 (0.44, 1.05)

0.43 (0.26, 0.73)

0.52 (0.33, 0.79)

0.37 (0.22, 0.62)

 Quintile 4 (> 29.25 ~ ≤ 35.25 μg/day)

109/54

0.59 (0.38, 0.90)

0.24 (0.14, 0.42)

0.44 (0.29, 0.68)

0.26 (0.15, 0.46)

 Quintile 5 (> 35.25 μg/day)

95/42

0.53 (0.33, 0.83)

0.09 (0.04, 0.19)

0.61 (0.39, 0.93)

0.43 (0.23, 0.82)

 P for trend

< 0.001

< 0.001

0.001

< 0.001

 Every 10-unit increment

0.87 (0.76, 1.00)

0.37 (0.27, 0.49)

0.9 (0.8, 1.02)

0.78 (0.63, 0.97)

 Quintile 1 (≤8.88 μg/day)

97/84

1.00

1.00

1.00

1.00

 Quintile 2 (> 8.88 ~ ≤ 10.85 μg/day)

92/70

0.88 (0.57, 1.35)

0.67 (0.41, 1.08)

0.66 (0.43, 1.02)

0.55 (0.33, 0.92)

 Quintile 3 (> 10.85 ~ ≤ 13.22 μg/day)

102/51

0.58 (0.37, 0.90)

0.42 (0.24, 0.72)

0.39 (0.25, 0.60)

0.25 (0.15, 0.43)

 Quintile 4 (> 13.22 ~ ≤ 16.55 μg/day)

88/65

0.85 (0.55, 1.32)

0.43 (0.24, 0.77)

0.51 (0.33, 0.78)

0.35 (0.20, 0.61)

 Quintile 5 (> 16.55 μg/day)

97/46

0.55 (0.35, 0.86)

0.15 (0.07, 0.32)

0.48 (0.31, 0.73)

0.30 (0.16, 0.58)

 P for trend

0.017

< 0.001

0.001

< 0.001

 Every 10-unit increment

0.90 (0.71, 1.13)

0.48 (0.30, 0.75)

0.89 (0.72, 1.09)

0.96 (0.67, 1.36)