Skip to main content

Table 4 Differences in CRC features and enzyme expression levels between colon and rectum

From: Correlation of cholesteryl ester metabolism to pathogenesis, progression and disparities in colorectal Cancer

 

Geographic and clinical information

Features

Colon

Rectum

Cases n (%)

61 (64.2)

34 (35.8)

% of Old (Young)

62.3 (37.7)

61.8 (38.2)

% of Female (Male)

49.2 (50.8)

47.1 (52.9)

% of AA (CA)*

63.9 (36.1)

47.1 (52.9)

% of + Margin (− Margin)

13.3 (86.7)

28.1 (71.9)

% High Stage (Low Stage)

63.9 (36.1)

60 (40)

% of Expired (Survived)

59 (41)

65 (35)

Survival time (month)**

46

56.4

 

Expression levels of CE metabolism related enzymes

Enzymes

Colon

Rectum

BCT

CRC

P value

BCT

CRC

P value

ACAT1 (n/mean ± SD)

53/5.3 ± 1.9

60/2.9 ± 2.2

0.0001

29/5.3 ± 2.2

25/4.6 ± 2.6

0.24

ACAT2 (n/mean ± SD)

49/5.4 ± 2.1

60/2.25 ± 1.8

0.71

26/5.5 ± 2.1

22/6.2 ± 1.9

0.54

NCEH1 (n/mean ± SD)

53/4.1 ± 1.9

60/4.3 ± 1.8

0.51

29/3.5 ± 2.0

26/4.2 ± 1.7

0.14

LAL (n/mean ± SD)

53/3.8 ± 1.7

55/6.27 ± 1.8

0.0001

2.9/3.6 ± 1.8

33/6.2 ± 1.3

0.0001

  1. * The difference is significant, P < 0.05. ** The time from diagnosis to date of expiration