Table 3 Levels of ceramides quantified in lean and obese groups (A and B) and that in after stratifying obese into obese-NDM and obese-DM groups (C and D)
Ceramides | Lean (A) | Obese (B) | P Value (A Vs B) | Obese-NDM (C) | Obese-DM (D) | P Value (C Vs D) |
|---|---|---|---|---|---|---|
N = 20 | N = 98 | N = 66 | N = 32 | |||
Mean ± SD (pg/mg) | Mean ± SD (pg/mg) | Mean ± SD (pg/mg) | Mean ± SD (pg/mg) | |||
C16-ceramide | 25.09 ± 9.67 | 38.56 ± 25.58 | 0.023* | 34.59 ± 12.08 | 46.75 ± 39.97 | 0.027* |
C16-dihydro-ceramide | 0.34 ± 0.12 | 0.53 ± 0.25 | < 0.005* | 0.51 ± 0.20 | 0.58 ± 0.33 | 0.198 |
C18-ceramide | 1.44 ± 0.45 | 1.63 ± 0.48 | 0.114 | 1.63 ± 0.45 | 1.62 ± 0.51 | 0.924 |
C18-dihydro-ceramide | 37.27 ± 4.89 | 41.96 ± 7.72 | 0.009* | 41.98 ± 6.75 | 41.90 ± 9.34 | 0.961 |
C18:1-ceramide | 0.43 ± 0.02 | 0.45 ± 0.07 | 0.153 | 0.45 ± 0.03 | 0.45 ± 0.11 | 0.925 |
C20-ceramide | 0.96 ± 0.44 | 1.23 ± 0.86 | 0.089 | 1.20 ± 0.56 | 1.29 ± 1.26 | 0.634 |
C22-ceramide | 9.15 ± 3.50 | 12.62 ± 9.39 | 0.109 | 12.30 ± 4.90 | 13.27 ± 14.79 | 0.635 |
C24:1-ceramide | 3.92 ± 1.54 | 6.20 ± 4.81 | 0.040* | 5.87 ± 2.87 | 6.99 ± 7.27 | 0.263 |