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Table 1 Baseline characteristics of recruited subjects in each hospital according to gallstone disease status

From: Blood lipid metabolism and the risk of gallstone disease: a multi-center study and meta-analysis

 

First Affiliated Hospital of Chongqing Medical University Jinshan Hospital

(n = 170,038)

The People’s Hospital of Kaizhou District of Chongqing (n = 372,289)

Tianjin Medical University Cancer Institute and Hospital (n = 10,940)

GSD

(n = 12,518)

Non-GSD

(n = 157,520)

Statistic

GSD

(n = 32,367)

Non-GSD

(n = 339,922)

Statistic

GSD

(n = 507)

Non-GSD

(n = 10,433)

Statistic

Age (year)

51.70 ± 13.48

41.00 ± 13.14

− 87.54**

52.01 ± 12.34

43.20 ± 12.96

− 122.02**

55.69 ± 13.76

42.88 ± 13.35

−21.08**

BMI (kg/m2)

24.54 ± 3.40

23.23 ± 3.43

−39.28**

25.18 ± 3.27

23.85 ± 3.46

−67.61**

NA

  

WC (cm)

84.43 ± 13.02

80.44 ± 27.62

−15.15**

85.52 ± 9.69

81.74 ± 10.18

−64.69**

NA

  

DBP (mmHg)

78.16 ± 12.08

74.48 ± 11.44

−31.29**

79.43 ± 12.69

76.88 ± 12.24

−32.48**

80.60 ± 12.20

76.49 ± 11.75

−7.49**

SBP (mmHg)

129.86 ± 19.48

122.75 ± 17.17

−37.66**

128.96 ± 19.67

122.84 ± 17.82

−50.38**

139.42 ± 20.81

127.44 ± 18.91

−12.40**

FBG (mmol/L)

5.81 ± 1.58

5.39 ± 1.11

−29.20**

5.99 ± 1.75

5.54 ± 1.27

−44.24**

6.37 ± 1.98

5.63 ± 1.15

−8.24**

AST (U/L)

23.91 ± 18.78

23.12 ± 15.02

−5.43**

26.63 ± 17.06

25.87 ± 16.01

−8.02**

20.58 ± 14.70

18.81 ± 8.85

−2.68*

ALT (U/L)

27.93 ± 25.21

26.63 ± 25.66

−5.41**

28.49 ± 26.01

27.14 ± 24.76

−9.20**

31.13 ± 24.61

26.95 ± 22.47

−4.05**

T-bil (umol/L)

13.89 ± 5.67

13.65 ± 5.37

−4.61**

15.28 ± 6.72

15.01 ± 5.97

−4.23**

16.88 ± 5.60

17.02 ± 5.55

0.56

Cr (umol/L)

141.17 ± 944.41

102.29 ± 651.11

−4.46**

69.59 ± 19.27

70.8 ± 18.28

10.61**

80.17 ± 10.07

78.97 ± 11.29

−2.34*

UA (umol/L)

347.66 ± 92.64

345.08 ± 96.22

−2.95*

341.92 ± 88.75

341.65 ± 91.32

−0.48

313.79 ± 79.39

303.33 ± 82.77

−2.78*

UN (mmol/L)

5.28 ± 1.45

5.08 ± 1.30

−15.30**

5.32 ± 1.47

5.19 ± 1.42

−15.30**

4.63 ± 1.20

4.41 ± 1.17

−4.25**

TC (mmol/L)

5.02 ± 1.00

4.88 ± 0.94

−15.26**

5.14 ± 1.03

5.02 ± 0.99

−20.39**

5.59 ± 1.04

5.35 ± 1.01

−5.22**

TG (mmol/L)

1.91 ± 1.84

1.58 ± 1.43

−19.63**

2.01 ± 1.86

1.71 ± 1.58

−27.74**

1.55 ± 0.92

1.33 ± 0.93

−5.25**

LDL-C (mmol/L)

3.04 ± 0.84

2.92 ± 0.81

−15.41**

2.05 ± 0.62

1.97 ± 0.63

−18.69**

NA

  

HDL-C (mmol/L)

1.36 ± 0.33

1.41 ± 0.34

15.35**

1.36 ± 0.37

1.40 ± 0.37

17.31**

NA

  

Female

6121 (48.9%)

70,846 (45.0%)

71.99**

18,143 (56.1%)

155,377 (45.7%)

1270.80**

265 (52.3%)

5861 (56.2%)

3.00

FLD

5162 (41.2%)

37,795 (24.0%)

1826.04**

13,261 (41.0%)

87,569 (25.8%)

3457.16**

274 (54.0%)

3180 (30.5)

124.26**

Kidney stones

679 (5.4%)

6279 (4.0%)

61.10**

1197 (3.7%)

10,475 (3.1%)

36.87**

22 (4.3%)

233 (2.3%)

9.42*

Hypertension

4169 (36.9%)

27,439 (19.6%)

1906.37**

9226 (32.7%)

62,264 (20.8%)

2130.90**

246 (50.9%)

2592 (26.3%)

139.7**

Gallstones

6173 (49.3%)

–

 

14,598 (45.1%)

–

 

361 (71.2%)

–

 

Cholecystectomy

6345 (50.7%)

–

 

17,769 (54.9%)

–

 

146 (28.8%)

–

 
  1. Quantitative data are presented as the mean ± SD, and the statistic is Z-value. Qualitative data are presented as N (%), and the statistic is Chi-square. GSD gallstone disease, BMI body mass index, WC waist circumference, DBP diastolic blood pressure, SBP systolic blood pressure, FBG fasting blood glycose, AST aspartate transaminase, ALT alanine transaminase, T-bil total bilirubin, Cr creatinine, UA uric Acid, UN urea nitrogen, TC total cholesterol, TG triglycerides, LDL low density lipoprotein cholesterol, HDL high density lipoprotein cholesterol, FLD Fatty liver disease. *P < 0.05; ** P < 0.001