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Table 1 Baseline characteristics of the study population stratified by tertiles of MHR value

From: Monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) and the risk of all-cause and cardiovascular mortality: a nationwide cohort study in the United States

 

Total

(n = 34,335)

MHR

P

< 0.009

(n = 11,537)

0.009–0.013

(n = 11,400)

> 0.013

(n = 11,398)

MHR

0.012 ± 0.006

0.006 ± 0.001

0.011 ± 0.001

0.018 ± 0.007

< 0.001

Age, year

49.6 ± 18.2

49.7 ± 17.7

49.1 ± 18.3

50.0 ± 18.6

< 0.001

Male, n (%)

16,601 (48.4%)

3671 (31.8%)

5527 (48.5%)

7403 (64.9%)

< 0.001

Ethnicity, n (%)

< 0.001

 Mexican American

6187 (18.0%)

1809 (15.7%)

2274 (19.9%)

2104 (18.5%)

 

 Non-Hispanic White

16,133 (47.0%)

4846 (42.0%)

5266 (46.2%)

6021 (52.8%)

 

 Non-Hispanic Black

6691 (19.5%)

2982 (25.8%)

2116 (18.6%)

1593 (14.0%)

 

 Others

5324 (15.5%)

1900 (16.5%)

1744 (15.3%)

1680 (14.7%)

 

Smoker, n (%)

15,975 (46.5%)

4490 (38.9%)

5209 (45.7%)

6276 (55.1%)

< 0.001

Drinker, n (%)

24,198 (70.5%)

7918 (68.6%)

8018 (70.3%)

8262 (72.5%)

< 0.001

Diabetes mellitus, n (%)

24,198 (70.5%)

911 (7.9%)

1327 (11.6%)

1640 (14.4%)

< 0.001

Hypertension, n (%)

11,722 (34.1%)

3524 (30.5%)

3849 (33.8%)

4349 (38.2%)

< 0.001

Heart failure, n (%)

1093 (3.2%)

235 (2.0%)

308 (2.7%)

550 (4.8%)

< 0.001

Coronary heart disease, n (%)

1450 (4.2%)

250 (2.2%)

479 (4.2%)

721 (6.3%)

< 0.001

Stroke, n (%)

1240 (3.6%)

335 (2.9%)

389 (3.4%)

516 (4.5%)

< 0.001

Cancer, n (%)

3078 (9.0%)

1013 (8.8%)

972 (8.5%)

1093 (9.6%)

0.013

Body mass index, kg/m2

28.8 ± 6.6

27.2 ± 6.4

28.9 ± 6.5

30.2 ± 6.6

< 0.001

White blood cell,103/μL

7.24 ± 2.42

6.15 ± 1.74

7.14 ± 1.83

8.45 ± 2.92

< 0.001

Monocyte,103/μL

0.55 ± 0.20

0.41 ± 0.11

0.54 ± 0.12

0.72 ± 0.22

< 0.001

Hemoglobin, g/dL

14.13 ± 1.54

13.75 ± 1.41

14.14 ± 1.53

14.52 ± 1.60

< 0.001

Platelets, 103/μL

252.31 ± 67.30

246.32 ± 65.60

252.31 ± 65.59

258.37 ± 70.11

< 0.001

Triglyceride, mg/dL

139.89 ± 106.77

106.29 ± 66.54

136.13 ± 92.17

177.66 ± 137.04

< 0.001

LDL-C, mg/dL

117.05 ± 36.14

116.08 ± 35.44

117.46 ± 36.24

117.61 ± 36.71

0.002

HDL-C, mg/dL

52.54 ± 15.85

64.83 ± 16.03

51.66 ± 11.05

40.98 ± 9.34

< 0.001

Albumin, g/dL

4.25 ± 0.35

4.26 ± 0.36

4.25 ± 0.35

4.25 ± 0.35

0.038

eGFR, mL/min/1.73 m2

95.13 ± 32.75

95.30 ± 33.43

96.05 ± 32.25

94.05 ± 32.52

< 0.001

All-cause mortality, n (%)

4310 (12.6%)

1181 (10.2%)

1328 (11.7%)

1801 (15.8%)

< 0.001

Cardiovascular mortality, n (%)

754 (2.2%)

165 (1.4%)

247 (2.2%)

342 (3.0%)

< 0.001

  1. eGFR estimated glomerular filtration rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, MHR monocyte-to-high-density lipoprotein-cholesterol ratio.
  2. Values are mean ± standardized deviation or number (%)