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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Delta-5® oil, containing the anti-inflammatory fatty acid sciadonic acid, improves skin barrier function in a skin irritation model in healthy female subjects

Fig. 2

Simplified Experimental Design. Shown are measurements and treatments applied to each subject’s forearm on days 0–28, in the order conducted (top of each box, down). Test site 1, Untreated control; Site 2, Untreated control, chemically damaged with 2% SLS; and Test Site 3, Delta-5 oil applied to SLS-damaged skin. TEWL (g/m2h) and NOVA Impedance (units are in arbitrary Dermal Phase Meter impedance units; DPMIU) were measured just before SLS was applied to the skin on Day 0 (baseline); and redness (measured by Visual Expert Grading Scores; VEGS) was measured just after SLS was applied to the skin on Day 0*. On Day 1, redness, TEWL and impedance values are measured 1 day after SLS injury, then Delta-5 oil is applied to the Delta-5 oil group, so that on Day 2, Delta-5 oil has been on the skin for 24 h. Redness was not measured on Day 2. D5 2X/d, Delta-5 oil applied twice per day (see text for further details)

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Lipids in Health and Disease

ISSN: 1476-511X