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Fig. 7 | Lipids in Health and Disease

Fig. 7

From: Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice

Fig. 7

Non-ceramide derived lipid class alterations observed in brain derived EVs from MLD and control mice. Scatter plots for different lipid classes that show a general trend with increasing time points of disease. The average of fold changes plotted for MLD (ARSA−/−) relative to control mice (ARSA+/+) at 30 postnatal days (P30), 3 months (3 m) and 6 months (6 m) of age are shown. A downward trend was observed in parallel with disease including A) fatty acids (FA), B) fatty acid ester of hydroxyl fatty acids, C) monogalactosyldiacylglycerols (MGDG), D) diacylglycerols (DG) and E) triacylglycerols (TG). N = 3 biological replicates per genotype and time point

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Lipids in Health and Disease

ISSN: 1476-511X