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Table 2 Mean values of various methods LDL-C and correlation with direct LDL-C

From: Evaluation of Sampson equation for LDL-C in acute coronary syndrome patients: a Chinese population-based cohort study

LDL-C

Formula

Mean ± SD

mg/dl (mmol/l)

Mean difference

mg/dl (mmol/l)

Correlation (r)

p value

Direct LDL-C

Directly measured

93.61 ± 29.33 (2.42 ± 0.76)

NA

1

< 0.001

Friedewald

LDL-C(mg/dl) = TC - HDL-C - TG/5

93.95 ± 35.55 (2.43 ± 0.92)

0.34 (0.01)

0.896

< 0.001

Sampson

LDL-C(mg/dl) = TC/0.948 - HDL-C/0.971 - (TG/8.56 + TG × Non-HDL-C/2140 - TG2/16,100) − 9.44

97.14 ± 34.27 (2.51 ± 0.89)

3.53 (0.09)

0.943

< 0.001

  1. LDL-C Low-density lipoprotein cholesterol, TG triglyceride