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Table 1 Baseline clinical characteristics of men and women with severe AS (n = 46)

From: Measures of high-density lipoprotein function in men and women with severe aortic stenosis

Clinical parameter Men (n = 30) Women (n = 16)
Age, (years) 70 (10) 68 (9.5)
BMI, kg/m2 25.19 (5.09)** 28.3 (8.25)*
Total Cholesterol, mmol/L (mg/dL) 4.8 (0.93)
189.6 (36)
5.3 (2.76)
205.7 (106.70)
TG, mmol/L (mg/dL) 1.5 (1.44)
132.0 (127.60)
2.2 (1.14)*
198.4 (101)
HDL-C, mmol/L (mg/dL) 1.2 (0.60)
47.2 (23.20)
1.3 (0.51)
48.8 (19.72)
LDL-C, mmol/L (mg/dL) 2.6 (0.70)
101.7 (27.23)
3.5 (2.49)*
136.7 (96.30)
Lp(a), μg/mL 102.0 (53) 118.4 (44)
Left ventricular ejection fraction, (%) 57.0 ± 12.86 54.0 ± 14.52
Pmax, mm Hg 58.2 ± 28.56** 50.5 ± 18.3
Pmean, mm Hg 32.8 ± 16.46* 28.5 ± 10
α-HDL size, (nm) 5.9 ± 0.60 6.7 ± 2.38
Preβ1-HDL, total spectral count 15,661.7 ± 789 20,298.3 ± 1076.15*
α-HDL, total spectral count 50,447.0 ± 546.52 63,006.0 ± 756.80**
Cholesterol Efflux, % 7.1 ± 0.38 8.2 ± 0.47**
LCAT activity, % 12.0 ± 8.07 16.5 ± 9.11*
  1. Continuous variables are presented as mean ± standard deviation or as median (interquartile range) if skewed. For cholesterol conversion to mg/dL multiply by 38.67 and for triglycerides, multiply by 88.57
  2. BMI body mass index, HDL-C high-density lipoprotein cholesterol, Pmax maximum pressure across the valve, Pmean mean pressure across the valve, LCAT Lecithin–cholesterol acyltransferase, LDL-C low-density lipoprotein cholesterol, Lp(a) lipoprotein(a), TG triglycerides
  3. *P < 0.05, **P < 0.01