Table 1 Baseline clinical characteristics of men and women with severe AS (n = 46)

Age, (years)

70 (10)

68 (9.5)

BMI, kg/m²

25.19 (5.09)**

28.3 (8.25)*

Total Cholesterol, mmol/L (mg/dL)

4.8 (0.93)

189.6 (36)

5.3 (2.76)

205.7 (106.70)

TG, mmol/L (mg/dL)

1.5 (1.44)

132.0 (127.60)

2.2 (1.14)*

198.4 (101)

HDL-C, mmol/L (mg/dL)

1.2 (0.60)

47.2 (23.20)

1.3 (0.51)

48.8 (19.72)

LDL-C, mmol/L (mg/dL)

2.6 (0.70)

101.7 (27.23)

3.5 (2.49)*

136.7 (96.30)

Lp(a), μg/mL

102.0 (53)

118.4 (44)

Left ventricular ejection fraction, (%)

57.0 ± 12.86

54.0 ± 14.52

Pmax, mm Hg

58.2 ± 28.56**

50.5 ± 18.3

Pmean, mm Hg

32.8 ± 16.46*

28.5 ± 10

α-HDL size, (nm)

5.9 ± 0.60

6.7 ± 2.38

Preβ1-HDL, total spectral count

15,661.7 ± 789

20,298.3 ± 1076.15*

α-HDL, total spectral count

50,447.0 ± 546.52

63,006.0 ± 756.80**

Cholesterol Efflux, %

7.1 ± 0.38

8.2 ± 0.47**

LCAT activity, %

12.0 ± 8.07

16.5 ± 9.11*