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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet

Fig. 5

Real-time PCR quantification of hepatic mRNAs in adult male wildtype (WT), HNF4α heterozygote (HET), and HNF4α knockout (KO) mice fed the high-fat-high-sugar diet (HFHS) for 15 d. A genes important in the differentiation and proliferation of hepatocytes and cholangiocytes; B transcriptional regulators; C genes important for cholesterol and bile acid metabolism; D genes important for apolipoprotein metabolism; E genes important in lipid metabolism; and F genes important for the metabolism of fatty acids and sugar. N=4-6, mean ± SE. Data were normalized to peroxiredoxin 1 (Prxd1), with wildtype values set at 1.0. * P < 0.05 versus WT mice

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