Skip to main content
Fig. 7 | Lipids in Health and Disease

Fig. 7

From: Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet

Fig. 7

Dual-luciferase assays of regulation of mouse Srebp-1c and human SREBP-1C promoters. Assays were conducted 24 h after HEK293 cells (A - C) or HepG2 cells (D) were transfected with firefly reporter vectors, pRL-CMV, and expression vectors for HNF4α, LXRα, or SHP. N=4 per group, mean ± SE. * P < 0.05 versus control; # P < 0.05 versus LXRα (A & B), wildtype (WT) HNF4α (C), or LXRα (D) alone; $ P < 0.05 versus LXRα + SHP group

Back to article page