Association of LDL:HDL ratio with prediabetes risk: a longitudinal observational study based on Chinese adults

Table 4 Stratified association between LDL:HDL ratio and prediabetes by age, sex, family history of diabetes and BMI

Subgroup	No. of cases	unadjusted HR (95%CI)	adjusted HR (95%CI)	P-interaction
Age (years)				0.0018
20–29	563 (5.32%)	1.27 (1.14, 1.42)	1.21 (1.06, 1.38)
30–39	3141 (8.11%)	1.20 (1.15, 1.25)	1.14 (1.07, 1.21)
40–49	2888 (12.30%)	1.15 (1.10, 1.20)	1.14 (1.07, 1.21)
50–59	2783 (18.16%)	1.00 (0.95, 1.05)	1.07 (1.01, 1.14)
60–69	2053 (23.32%)	0.87 (0.82, 0.93)	1.00 (0.92, 1.08)
≥ 70	924 (27.30%)	0.94 (0.86, 1.04)	1.04 (0.93, 1.16)
Sex				< 0.0001
Men	7735 (14.84%)	0.98 (0.95, 1.00)	1.02 (0.97, 1.07)
Women	4617 (9.58%)	1.23 (1.20, 1.26)	1.17 (1.12, 1.22)
Family history of diabetes				0.0066
Yes	310 (14.04%)	1.34 (1.18, 1.53)	1.32 (1.15, 1.51)
No	12,042 (12.28%)	1.14 (1.12, 1.17)	1.09 (1.04, 1.14)
BMI (kg/m²)				< 0.0001
< 18.5	288 (5.04%)	1.32 (1.14, 1.53)	1.26 (1.08, 1.47)
18.5–23.9	5399 (9.44%)	1.16 (1.13, 1.19)	1.15 (1.10, 1.20)
24–27.9	5080 (16.94%)	0.92 (0.89, 0.96)	1.03 (0.98, 1.09)
≥ 28	1585 (21.44%)	0.81 (0.76, 0.87)	0.96 (0.89, 1.03)
TG (mmol/L)				0.9010
< 1.7	8276 (10.52%)	1.16 (1.13, 1.19)	1.06 (0.99, 1.13)
≥ 1.7	4076 (18.82%)	1.06 (0.99, 1.13)	1.07 (0.99, 1.15)

Abbreviations: HR hazard ratios, other abbreviations as in Table 1
Note: Models adjusted for the same covariates as in model 3 (Table 2), except for the stratification variable

ISSN: 1476-511X