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Table 4 Stratified association between LDL:HDL ratio and prediabetes by age, sex, family history of diabetes and BMI

From: Association of LDL:HDL ratio with prediabetes risk: a longitudinal observational study based on Chinese adults

Subgroup No. of cases unadjusted HR (95%CI) adjusted HR (95%CI) P-interaction
Age (years)     0.0018
 20–29 563 (5.32%) 1.27 (1.14, 1.42) 1.21 (1.06, 1.38)  
 30–39 3141 (8.11%) 1.20 (1.15, 1.25) 1.14 (1.07, 1.21)  
 40–49 2888 (12.30%) 1.15 (1.10, 1.20) 1.14 (1.07, 1.21)  
 50–59 2783 (18.16%) 1.00 (0.95, 1.05) 1.07 (1.01, 1.14)  
 60–69 2053 (23.32%) 0.87 (0.82, 0.93) 1.00 (0.92, 1.08)  
  ≥ 70 924 (27.30%) 0.94 (0.86, 1.04) 1.04 (0.93, 1.16)  
Sex     < 0.0001
 Men 7735 (14.84%) 0.98 (0.95, 1.00) 1.02 (0.97, 1.07)  
 Women 4617 (9.58%) 1.23 (1.20, 1.26) 1.17 (1.12, 1.22)  
Family history of diabetes     0.0066
 Yes 310 (14.04%) 1.34 (1.18, 1.53) 1.32 (1.15, 1.51)  
 No 12,042 (12.28%) 1.14 (1.12, 1.17) 1.09 (1.04, 1.14)  
BMI (kg/m2)     < 0.0001
  < 18.5 288 (5.04%) 1.32 (1.14, 1.53) 1.26 (1.08, 1.47)  
 18.5–23.9 5399 (9.44%) 1.16 (1.13, 1.19) 1.15 (1.10, 1.20)  
 24–27.9 5080 (16.94%) 0.92 (0.89, 0.96) 1.03 (0.98, 1.09)  
  ≥ 28 1585 (21.44%) 0.81 (0.76, 0.87) 0.96 (0.89, 1.03)  
TG (mmol/L)     0.9010
  < 1.7 8276 (10.52%) 1.16 (1.13, 1.19) 1.06 (0.99, 1.13)  
  ≥ 1.7 4076 (18.82%) 1.06 (0.99, 1.13) 1.07 (0.99, 1.15)  
  1. Abbreviations: HR hazard ratios, other abbreviations as in Table 1
  2. Note: Models adjusted for the same covariates as in model 3 (Table 2), except for the stratification variable