Associations of maternal lipoprotein particle distribution in mid-pregnancy with birth outcomes: a pilot study

Table 2 Association between maternal second trimester lipid profile and pregnancy outcomes

Lipid exposure	Birth weight (g) β (95% CI)^* N = 25	P-value	Gestational age (weeks) β (95% CI)^* N = 25	P-value
Total-C (mg/dL)
Model 1	-0.80 (-4.20,2.60)	0.65	0.003 (-0.01,0.01)	0.57
Model 2	-0.40 (-3.80,3.00)	0.82	0.001 (-0.01,0.01)	0.81
LDL-C (mg/dL)
Model 1	0.40 (-4.00,4.80)	0.86	0.002 (-0.01,0.01)	0.74
Model 2	0.70 (-3.60,5.00)	0.75	0.001 (-0.01,0.01)	0.88
HDL-C (mg/dL)
Model 1	-4.90 (-11.10,1.20)	0.12	0.003 (-0.01,0.02)	0.73
Model 2	-4.20 (-10.60,2.30)	0.21	-0.002 (-0.02,0.02)	0.85
nonHDL-C (mg/dL)
Model 1	0.80 (-3.20,4.80)	0.69	0.003 (-0.01,0.01)	0.65
Model 2	0.90 (-3.00,4.70)	0.66	0.002 (-0.01,0.01)	0.69
Triglycerides (mg/dL)
Model 1	1.40 (-1.40,4.10)	0.32	0.003 (0.00,0.01)	0.45
Model 2	1.10 (-1.70,3.80)	0.45	0.005 (0.00,0.01)	0.21
ApoB (mg/dL)
Model 1	1.30 (-4.90,7.50)	0.67	0.002 (-0.01,0.02)	0.78
Model 2	1.50 (-4.60,7.50)	0.63	0.002 (-0.01,0.02)	0.83

^*Values are beta coefficients (95% CI) derived from linear regression models, representing the change in birth weight (g) or gestational age (weeks) with one unit increment in each lipid exposure; Model 1: crude model; Model 2: adjusted for maternal pre-pregnancy BMI

ISSN: 1476-511X