Associations of maternal lipoprotein particle distribution in mid-pregnancy with birth outcomes: a pilot study

Table 4 Association between maternal second trimester LDL lipoprotein profile and pregnancy outcomes

Lipid exposure	Birth weight (g) β (95% CI)^* N = 25	P-value	Gestational age (weeks) β (95% CI)^* N = 25	P-value
Total LDL particles (nM)
Model 1	0.20 (-0.30,0.70)	0.42	0.00 (0.00,0.00)	0.70
Model 2	0.20 (-0.20,0.70)	0.37	0.00 (0.00,0.00)	0.76
Small LDL particles (nM)
Model 1	0.00 (-0.50,0.50)	0.93	-0.001 (0.00,0.00)	0.11
Model 2	-0.10 (-0.60,0.40)	0.64	-0.001 (0.00,0.00)	0.24
Intermediate LDL particles (nM)
Model 1	0.30 (-0.50,1.10)	0.47	0.002 (0.00,0.00)	0.09
Model 2	0.30 (-0.50,1.10)	0.44	0.002 (0.00,0.00)	0.08
Large LDL particles (nM)
Model 1	0.10 (-0.30,0.50)	0.66	0.001 (0.00,0.00)	0.37
Model 2	0.20 (-0.20,0.70)	0.38	0.001 (0.00,0.00)	0.67
LDL size (nm)
Model 1	-141.50 (-386.80,103.80)	0.26	0.466 (-0.18,1.11)	0.16
Model 2	-111.80 (-362.10,138.60)	0.38	0.348 (-0.30,1.00)	0.20

^*Values are beta coefficients (95% CI) derived from linear regression models, representing the change in birth weight (g) or gestational age (weeks) with one unit increment in each lipid exposure; Model 1: crude model; Model 2: adjusted for maternal pre-pregnancy BMI

ISSN: 1476-511X