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Table 5 Association between maternal second trimester HDL lipoprotein profile and pregnancy outcomes

From: Associations of maternal lipoprotein particle distribution in mid-pregnancy with birth outcomes: a pilot study

Lipid exposure

Birth weight (g) β (95% CI)* N = 25

P-value

Gestational age (weeks) β (95% CI)* N = 25

P-value

Total HDL particles (μM)

 Model 1

-20.90 (-37.80,-3.90)

0.02

-0.009 (-0.06,0.05)

0.75

 Model 2

-19.40 (-36.70,-2.20)

0.03

-0.018 (-0.07,0.03)

0.51

Small HDL particles (μM)

 Model 1

2.60 (-24.20,29.50)

0.85

-0.033 (-0.10,0.04)

0.36

Model 2

1.00 (-25.30,27.40)

0.94

-0.027 (-0.09,0.04)

0.43

Medium HDL particles (μM)

 Model 1

-14.30 (-34.50,6.00)

0.17

0.003 (-0.06,0.05)

0.93

 Model 2

-12.80 (-32.90,7.30)

0.21

-0.001 (-0.06,0.04)

0.73

Large HDL particles (μM)

 Model 1

-19.60 (-56.80,17.50)

0.30

0.044 (-0.06,0.14)

0.39

 Model 2

-15.50 (-53.10,22.00)

0.42

0.027 (-0.07,0.13)

0.59

HDL size (nm)

 Model 1

55.80 (-361.80,473.30)

0.79

0.923 (-0.13,1.98)

0.09

 Model 2

107.60 (-306.40,521.60)

0.61

0.773 (-0.27,1.81)

0.14

  1. *Values are beta coefficients (95% CI) derived from linear regression models, representing the change in birth weight (g) or gestational age (weeks) with one unit increment in each lipid exposure; Model 1: crude model; Model 2: adjusted for maternal pre-pregnancy BMI
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Lipids in Health and Disease

ISSN: 1476-511X