Characteristic | T2DM without CAD(n = 249) | T2DM with CAD(n = 253) | p value |
---|---|---|---|
Clinical variables | |||
 Age (years) | 51(42,59) | 59(53,67) | < 0.001 |
 Male (%) | 54.15 | 48.19 | 0.182 |
 Diabetic durations (years) | 1(0,4) | 3(0,6) | < 0.001 |
 BMI | 24.04 ± 0.11 | 24.93 ± 0.14 | 0.002 |
Medical history (n, %) | |||
 Smoking (%) | 20.95 | 18.07 | 0.432 |
 Alcohol drinking (%) | 14.22 | 13.65 | 0.853 |
 Hypertension (%) | 32.41 | 28.92 | 0.396 |
Medication (n, %) | |||
 Insulin (%) | 62.06 | 69.48 | 0.080 |
 Metformin (%) | 47.04 | 50.60 | 0.424 |
 Anti-hypertension | 28.85 | 23.69 | 0.189 |
Laboratory variables | |||
 WBC (×  109/L) | 6.09(5.18,7.02) | 7.31(5.95,8.64) | < 0.001 |
 NEU (× 109/L) | 3.30(2.66,4.07) | 4.53(3.02,6.07) | < 0.001 |
 LYM (× 109/L) | 1.95(1.55,2.39) | 1.73(1.28,2.15) | < 0.001 |
 NLR ratio | 1.66(1.30,2.15) | 2.50(1.61,4.24) | < 0.001 |
 hsCRP (mg/dl) | 0.80(0.34,2.56) | 1.69(0.64,3.74) | < 0.001 |
 HbA1c (%) | 8.5(6.8,10,4) | 8.8(7.5,9.0) | 0.334 |
 FPG (mmol/L) | 9.76(7.03,12.22) | 9.04(7.52,11.45) | 0.569 |
 2hPG (mmol/L) | 14.37(10.99,18.81) | 18.31(13.22,21.82) | < 0.001 |
 GA (g/L) | 9.54(6.86, 12.30) | 10.76(8.97,12.74) | < 0.001 |
 GA/ALB (%) | 0.234(0.174,0.299) | 0.354(0.307,0.407) | < 0.001 |
 ALT (U/L) | 19(14,28) | 21(15.29) | 0.065 |
 AST (U/L) | 17(13,22) | 21(16.27) | < 0.001 |
 GGT (U/L) | 27(18,32) | 28(19,36) | 0.968 |
 Urea (mmol/L) | 5.44(4.50,6.35) | 5.88(4.75,7.08) | < 0.001 |
 Cr (μmol/L) | 64(57,72) | 73(64,82) | < 0.001 |
 UA (μmol/L) | 350(288,423) | 342(286,423) | 0.614 |
 eGFR (ml/min/1.73m2) | 108.35(98.77,116.57) | 97.63(90.48,106.22) | < 0.001 |
 FFA (mmol/L) | 0.31(0.20,0.45) | 0.54(0.34,0.91) | < 0.001 |
 TC (mmol/L) | 4.56(3.86,5.17) | 4.47(3.79,5.31) | 0.909 |
 TG (mmol/L) | 1.60(1.12,2.87) | 1.56(1.02,2.30) | 0.135 |
 HDL-C (mmol/L) | 0.96(0.82,1.17) | 0.89(0.77,1.07) | 0.002 |
 LDL-C (mmol/L) | 2.53(1.91,3.22) | 2.40(1.68,3.23) | 0.347 |
 Apo A1 (g/L) | 1.22(1.09,1.35) | 1.17(1.05,1.28) | 0.003 |
 Apo B (g/L) | 0.82(0.69,0.95) | 0.90(0.74,1.02) | < 0.001 |
 Apo B/Apo A1 ratio | 0.68(0.55,0.81) | 0.78(0.60,0.91) | 0.001 |
 GDF-15 (pg/dl) | 7.88(5.92,10.11) | 13.84(9.43,18.41) | < 0.001 |