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Table 1 Characteristics of PNEN patients

From: The associations between serum high-density lipoprotein cholesterol levels and malignant behavior in pancreatic neuroendocrine neoplasms

Characteristics Classification 1 Classification 2
G1 (n = 66) G2/G3 (n = 131) P-value G1/G2 (n = 151) G3 (n = 46) P-value
Sex (n)    0.245    0.003
 Male 31 73   71 33  
 Female 35 58 80 13  
Age (yr) 53.50 ± 11.38 57.34 ± 11.62 0.029 54.73 ± 11.81 60..41 ± 10.06 0.002
Location    0.175    0.668
 Head-neck 37 56   69 24  
 Body 17 49 53 13  
 Tail 12 26 29 9  
Tumor size (cm)a 1.5(1.2–2.43) 3.5(2.5–4.9) < 0.001 2.5(1.5–3.9) 3.65(2.98–5.5) < 0.001
Lymph    0.026    0.004
 Yes 2 17   9 10  
 No 64 114 142 36  
Vascular invasion    0.001    < 0.001
 Yes 2 26   14 14  
 No 64 105 137 32  
Organs invasion    < 0.001    0.044
 Yes 0 29   18 11  
 No 66 102 133 35  
Neural invasion    0.019    0.009
 Yes 2 18   10 10  
 No 64 113   141 36  
Glu(mmol/L) 5.12 ± 1.09 5.75 ± 2.09 0.009 5.49 ± 1.98 5.69 ± 1.24 0.036
TG (mmol/L) 1.41 ± 0.87 1.37 ± 0.83 0.494 1.37 ± 0.86 1.42 ± 0.80 0.712
TC (mmol/L) 4.49 ± 1.00 4.27 ± 1.09 0.173 4.30 ± 1.03 4.49 ± 1.14 0.206
HDL-c (mmol/L) 1.23 ± 0.37 1.11 ± 0.36 0.031 1.16 ± 0.35 1.09 ± 0.41 0.511
 HDL-c ≤ 0.9 (mmol/L) 10 38 0.032 31 17 0.023
 HDL-c > 0.9 (mmol/L) 56 93 120 29
LDL (mmol/L) 2.56 ± 0.75 2.39 ± 0.84 0.183 2.45 ± 0.80 2.42 ± 0.87 0.928
DM       0.367
 Yes 10 32   30 12  
 No 56 99 121 34  
  1. DM Diabetes mellitus, Glu Glucose, HDL-c High density lipoprotein-cholesterol, PNEN Pancreatic neuroendocrine neoplasm, TG Triglyceride, TC Total cholesterol
  2. aData was shown as median (IQR) and analyzed using Mann-Whitney U-test