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Table 1 Characteristics of PNEN patients

From: The associations between serum high-density lipoprotein cholesterol levels and malignant behavior in pancreatic neuroendocrine neoplasms

Characteristics

Classification 1

Classification 2

G1 (n = 66)

G2/G3 (n = 131)

P-value

G1/G2 (n = 151)

G3 (n = 46)

P-value

Sex (n)

  

0.245

  

0.003

 Male

31

73

 

71

33

 

 Female

35

58

80

13

 

Age (yr)

53.50 ± 11.38

57.34 ± 11.62

0.029

54.73 ± 11.81

60..41 ± 10.06

0.002

Location

  

0.175

  

0.668

 Head-neck

37

56

 

69

24

 

 Body

17

49

53

13

 

 Tail

12

26

29

9

 

Tumor size (cm)a

1.5(1.2–2.43)

3.5(2.5–4.9)

< 0.001

2.5(1.5–3.9)

3.65(2.98–5.5)

< 0.001

Lymph

  

0.026

  

0.004

 Yes

2

17

 

9

10

 

 No

64

114

142

36

 

Vascular invasion

  

0.001

  

< 0.001

 Yes

2

26

 

14

14

 

 No

64

105

137

32

 

Organs invasion

  

< 0.001

  

0.044

 Yes

0

29

 

18

11

 

 No

66

102

133

35

 

Neural invasion

  

0.019

  

0.009

 Yes

2

18

 

10

10

 

 No

64

113

 

141

36

 

Glu(mmol/L)

5.12 ± 1.09

5.75 ± 2.09

0.009

5.49 ± 1.98

5.69 ± 1.24

0.036

TG (mmol/L)

1.41 ± 0.87

1.37 ± 0.83

0.494

1.37 ± 0.86

1.42 ± 0.80

0.712

TC (mmol/L)

4.49 ± 1.00

4.27 ± 1.09

0.173

4.30 ± 1.03

4.49 ± 1.14

0.206

HDL-c (mmol/L)

1.23 ± 0.37

1.11 ± 0.36

0.031

1.16 ± 0.35

1.09 ± 0.41

0.511

 HDL-c ≤ 0.9 (mmol/L)

10

38

0.032

31

17

0.023

 HDL-c > 0.9 (mmol/L)

56

93

120

29

LDL (mmol/L)

2.56 ± 0.75

2.39 ± 0.84

0.183

2.45 ± 0.80

2.42 ± 0.87

0.928

DM

     

0.367

 Yes

10

32

 

30

12

 

 No

56

99

121

34

 
  1. DM Diabetes mellitus, Glu Glucose, HDL-c High density lipoprotein-cholesterol, PNEN Pancreatic neuroendocrine neoplasm, TG Triglyceride, TC Total cholesterol
  2. aData was shown as median (IQR) and analyzed using Mann-Whitney U-test
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Lipids in Health and Disease

ISSN: 1476-511X