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Table 2 Associated factors of PNENs grade

From: The associations between serum high-density lipoprotein cholesterol levels and malignant behavior in pancreatic neuroendocrine neoplasms

Variables

G2/G3 vs G1 (model 1)

G3 vs G1/G2 (model 2)

Univariate

OR (95%CI)

p

Multivariate

OR (95%CI)

p

Univariate

OR (95%CI)

p

Multivariate

OR (95%CI)

p

Age (year)

1.03 (1.00–1.06)

0.031

1.05 (1.02–1.09)

< 0.01

1.05 (1.02–1.08)

< 0.01

1.06 (1.02–1.10)

< 0.01

Tumor size (cm)

2.51 (1.83–3.43)

< 0.01

2.46 (1.76–3.46)

< 0.01

1.31 (1.12–1.53)

< 0.01

1.30 (1.10–1.55)

< 0.01

HDL-c (mmol/L)

0.41 (0.18–0.93)

0.033

0.35 (0.12–1.00)

0.049

0.56 (0.22–1.41)

0.22

/

 

HDL-c (≤ 0.9 vs > 0.9 mmol/L)

2.29 (1.06–4.95)

0.035

/

 

2.27 (1.11–4.65)

0.025

2.51 (1.12–5.60)

0.02

Glucose level (mmol/L)

1.38 (1.04–1.82)

0.025

1.18 (0.85–1.64)

0.35

1.06 (0.89–1.25)

0.52

1.01 (0.84–1.21)

0.91

Vascular invasion

7.92 (1.82–34.51)

 

5.06 (1.02–25.23)

0.048

4.28 (1.86–9.87)

< 0.01

3.85 (1.53–9.70)

< 0.01

  1. “/” means that the variables were not included in the regression analysis
  2. CI Confidence interval, HDL-c High density lipoprotein-cholesterol, PNENs Pancreatic neuroendocrine neoplasms