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Table 2 Associated factors of PNENs grade

From: The associations between serum high-density lipoprotein cholesterol levels and malignant behavior in pancreatic neuroendocrine neoplasms

Variables G2/G3 vs G1 (model 1) G3 vs G1/G2 (model 2)
Univariate
OR (95%CI)
p Multivariate
OR (95%CI)
p Univariate
OR (95%CI)
p Multivariate
OR (95%CI)
p
Age (year) 1.03 (1.00–1.06) 0.031 1.05 (1.02–1.09) < 0.01 1.05 (1.02–1.08) < 0.01 1.06 (1.02–1.10) < 0.01
Tumor size (cm) 2.51 (1.83–3.43) < 0.01 2.46 (1.76–3.46) < 0.01 1.31 (1.12–1.53) < 0.01 1.30 (1.10–1.55) < 0.01
HDL-c (mmol/L) 0.41 (0.18–0.93) 0.033 0.35 (0.12–1.00) 0.049 0.56 (0.22–1.41) 0.22 /  
HDL-c (≤ 0.9 vs > 0.9 mmol/L) 2.29 (1.06–4.95) 0.035 /   2.27 (1.11–4.65) 0.025 2.51 (1.12–5.60) 0.02
Glucose level (mmol/L) 1.38 (1.04–1.82) 0.025 1.18 (0.85–1.64) 0.35 1.06 (0.89–1.25) 0.52 1.01 (0.84–1.21) 0.91
Vascular invasion 7.92 (1.82–34.51)   5.06 (1.02–25.23) 0.048 4.28 (1.86–9.87) < 0.01 3.85 (1.53–9.70) < 0.01
  1. “/” means that the variables were not included in the regression analysis
  2. CI Confidence interval, HDL-c High density lipoprotein-cholesterol, PNENs Pancreatic neuroendocrine neoplasms