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Table 3 Delta change in serum levels of lipids [μg mL−1 serum] after 4 week treatments. Only lipids that change significantly differently between treatments are shown. The Spearman’s correlation between median serum change in lipid per treatment group and content of lipids in the corresponding food products is represented by a letter code: +: weak positive (rho < 0.6); ++ moderate positive (rho 0.7–0.9); +++: strong positive (rho > 0.9). All correlations are positive

From: Molecular effects of the consumption of margarine and butter varying in trans fat composition: a parallel human intervention study

Fatty Acids Median wTFA IQR wTFA (Q1, Q3) Median iTFA IQR iTFA (Q1, Q3) Median rTFA IQR rTFA (Q1, Q3) PFDR-adjusted# sp
[μg mL−1] (n = 14)   (n = 14)   (n = 14)    
SFA
 C12:0 10b −15, 45 0b −10, 15 -60a −70, − 17.5 ** +
 C15:0 0a −10, 10 -5a −17.5, 7.5 30b 20, 40 *** ++
 C17:0 5a −10, 17.5 -5a −17.5, 10 35b 30, 82.5 ** ++
 C18:0 30a − 368, 583 -125a −320, 300 660b 190, 1783 * +
 12Me-C15:0 0a 10, 0 0a −10, 0 10b 10, 20 ** ++
 14Me-C16:0 0a −7.5, 10 0a 0, 10 10b 10, 20 ** ++
 15Me-C17:0 0a −7.5, 10 5a −10, 10 30b 2.5, 50 * ++
PUFA cis
 C20:4c 0a 0, 10 -5a −10, 0 20b 10, 35 ** ++
 C20:5c 15a 0, 42.5 -10a −5, 37.5 65b 30, 153 ** ++
 C22:5c 10a −10, 27.5 -10a −20, 15 60b 32.5, 128 *** ++
TFA
 C16:1 t9 0a 0, 10 0a −10, 10 25b 10, 47.5 ** ++
 C18:1 t6 + t7 + t8 + t9 10a −17.5, 10 115b 92.5, 185 10a −7.5, 20 ** +++
 C18:1 t10 + t11 0a −10, 10 75b 27.5, 90 115c 95, 153 *** +++
 C18:1 t12 0a 0, 0 25b 12.5, 30 10b 0, 17.5 ** ++
 C18:1 t13 + c6 + c7 0a 0, 10 30b 12.5, 38 20b 12.5, 30 ** +
 C18:2u 0a −10, 7.5 0a −10, 0 10b 10, 17.5 ** ++
 C18:2 t9 + c12 0b 0, 7.5 -5a −10, 0 10b 0, 10 ** +++
 C18:2c9 + t11 0a −10, 7.5 0a −17.5, 7.5 80b 52.5, 105 ** ++
Sum parameters
 Total C18:1 t 10a −7.5, 27.5 285b 163, 335 155b 103, 198 *** +
 Total C18:2 t (with CLA) -5a −17.5, 0 0a −27.5, 10 80b 40, 123 *** ++
 Total CLA −10a -10, 10 0a −17.5, 10 75b 45, 115 *** ++
 Total TFA (without CLA) 20a −7.5, 47.5 275b 115, 328 165b 125, 225 *** +
 Total TFA (with CLA) 20a −10, 62.5 290b 77.5, 338 225b 172.5, 337.5 *** +
 Total ω-3 FA 90ab −40, 228 -15a −200, 135 260b 102.5, 908 * ++
  1. Legend: #Kruskal wallis test results (PFDR-adjusted < 0.05: *, PFDR-adjusted < 0.01: **, PFDR-adjusted < 0.001: ***). Different letters (a, b, c) denote significant differences between treatment based on paired Wilcoxon signed-rank test (PFDR-adjusted < 0.05)
  2. Abbreviation: sp Spearman correlation, IQR Interquartile range. The FAs isomers that cannot be separated by the chromatographic steps are indicated by the plus sign “+” joining various cis (c) and/or trans (t) forms of the FAs